Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid- levels in vitro and in vivo

Medicine & Life Sciences

• latrepirdine 100%
• Amyloid 50%
• In Vitro Techniques 23%
• Transgenic Mice 10%
• Alzheimer Disease 9%
• Therapeutics 8%
• Cognition 6%
• Pharmaceutical Preparations 5%
• Neurons 5%
• Histamine Antagonists 4%
• Extracellular Fluid 4%
• Protein Transport 4%
• Conditioned Culture Medium 4%
• Neuroblastoma 4%
• Intraperitoneal Injections 3%
• Membrane Proteins 3%
• Rodentia 3%
• Hippocampus 3%
• Peptides 2%
• Brain 1%