Acute effects of drug abuse in schizophrenic patients: Clinical observations and patients' self-reports

Lisa Dixon, Gretchen Haas, Peter Weiden, John Sweeney, Allen Frances

Research output: Contribution to journalArticle

172 Citations (Scopus)

Abstract

Substance abuse among schizophrenic patients is an increasingly recognized clinical phenomenon. The authors review experimental and observed clinical effects of drug abuse and patients' subjective experiences of acute intoxication. Though drug abuse may exacerbate psychotic symptoms, abused drugs may also lead to transient symptom reduction in subgroups of schizophrenic patients. Some patients report feeling less dysphoric, less anxious, and more energetic while intoxicated. Models of the relationship of drug abuse and schizophrenia, particularly the self-medication hypothesis, are discussed in reference to these data.

Original languageEnglish (US)
Pages (from-to)69-79
Number of pages11
JournalSchizophrenia Bulletin
Volume16
Issue number1
DOIs
StatePublished - 1990

Fingerprint

Acute
Self Report
Substance-Related Disorders
Drugs
drugs
intoxication
schizophrenia
sensory feedback
Self Medication
subgroups
Schizophrenia
Emotions
Subgroup
Observation
Drug abuse
Self-report
Pharmaceutical Preparations
Model

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Public Health, Environmental and Occupational Health
  • Radiation
  • Radiological and Ultrasound Technology
  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Acute effects of drug abuse in schizophrenic patients : Clinical observations and patients' self-reports. / Dixon, Lisa; Haas, Gretchen; Weiden, Peter; Sweeney, John; Frances, Allen.

In: Schizophrenia Bulletin, Vol. 16, No. 1, 1990, p. 69-79.

Research output: Contribution to journalArticle

Dixon, Lisa ; Haas, Gretchen ; Weiden, Peter ; Sweeney, John ; Frances, Allen. / Acute effects of drug abuse in schizophrenic patients : Clinical observations and patients' self-reports. In: Schizophrenia Bulletin. 1990 ; Vol. 16, No. 1. pp. 69-79.
@article{c4d423bdefc24776bcf47b758a3687e0,
title = "Acute effects of drug abuse in schizophrenic patients: Clinical observations and patients' self-reports",
abstract = "Substance abuse among schizophrenic patients is an increasingly recognized clinical phenomenon. The authors review experimental and observed clinical effects of drug abuse and patients' subjective experiences of acute intoxication. Though drug abuse may exacerbate psychotic symptoms, abused drugs may also lead to transient symptom reduction in subgroups of schizophrenic patients. Some patients report feeling less dysphoric, less anxious, and more energetic while intoxicated. Models of the relationship of drug abuse and schizophrenia, particularly the self-medication hypothesis, are discussed in reference to these data.",
author = "Lisa Dixon and Gretchen Haas and Peter Weiden and John Sweeney and Allen Frances",
year = "1990",
doi = "10.1093/schbul/16.1.69",
language = "English (US)",
volume = "16",
pages = "69--79",
journal = "Schizophrenia Bulletin",
issn = "0586-7614",
publisher = "Oxford University Press",
number = "1",

}

TY - JOUR

T1 - Acute effects of drug abuse in schizophrenic patients

T2 - Clinical observations and patients' self-reports

AU - Dixon, Lisa

AU - Haas, Gretchen

AU - Weiden, Peter

AU - Sweeney, John

AU - Frances, Allen

PY - 1990

Y1 - 1990

N2 - Substance abuse among schizophrenic patients is an increasingly recognized clinical phenomenon. The authors review experimental and observed clinical effects of drug abuse and patients' subjective experiences of acute intoxication. Though drug abuse may exacerbate psychotic symptoms, abused drugs may also lead to transient symptom reduction in subgroups of schizophrenic patients. Some patients report feeling less dysphoric, less anxious, and more energetic while intoxicated. Models of the relationship of drug abuse and schizophrenia, particularly the self-medication hypothesis, are discussed in reference to these data.

AB - Substance abuse among schizophrenic patients is an increasingly recognized clinical phenomenon. The authors review experimental and observed clinical effects of drug abuse and patients' subjective experiences of acute intoxication. Though drug abuse may exacerbate psychotic symptoms, abused drugs may also lead to transient symptom reduction in subgroups of schizophrenic patients. Some patients report feeling less dysphoric, less anxious, and more energetic while intoxicated. Models of the relationship of drug abuse and schizophrenia, particularly the self-medication hypothesis, are discussed in reference to these data.

UR - http://www.scopus.com/inward/record.url?scp=0025373449&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025373449&partnerID=8YFLogxK

U2 - 10.1093/schbul/16.1.69

DO - 10.1093/schbul/16.1.69

M3 - Article

C2 - 2185536

AN - SCOPUS:0025373449

VL - 16

SP - 69

EP - 79

JO - Schizophrenia Bulletin

JF - Schizophrenia Bulletin

SN - 0586-7614

IS - 1

ER -