Acute Liver Failure

Shannan R. Tujios; William M. Lee

doi:10.1002/9781444341294.ch5

Acute Liver Failure

Shannan R. Tujios, William M. Lee

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.

Original language	English (US)
Title of host publication	Sherlock's Diseases of the Liver and Biliary System, 12th Edition
Publisher	Wiley-Blackwell
Pages	70-93
Number of pages	24
ISBN (Print)	9781405134897
DOIs	https://doi.org/10.1002/9781444341294.ch5
State	Published - May 5 2011

Keywords

Coagulopathy
Complication
Encephalopathy
Fulminant hepatitis
Intensive care
Mental status

ASJC Scopus subject areas

General Medicine

Access to Document

10.1002/9781444341294.ch5

Cite this

@inbook{935c05bba2d140f3a3f966be3fafdae8,

title = "Acute Liver Failure",

abstract = "Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.",

keywords = "Coagulopathy, Complication, Encephalopathy, Fulminant hepatitis, Intensive care, Mental status",

author = "Tujios, {Shannan R.} and Lee, {William M.}",

year = "2011",

month = may,

day = "5",

doi = "10.1002/9781444341294.ch5",

language = "English (US)",

isbn = "9781405134897",

pages = "70--93",

booktitle = "Sherlock's Diseases of the Liver and Biliary System, 12th Edition",

publisher = "Wiley-Blackwell",

}

TY - CHAP

T1 - Acute Liver Failure

AU - Tujios, Shannan R.

AU - Lee, William M.

PY - 2011/5/5

Y1 - 2011/5/5

N2 - Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.

AB - Rapid deterioration of hepatic function, characterized by coagulopathy and mental status changes, defines acute liver failure. There are numerous causes of acute liver failure which vary by geographic region. Survival depends on rapid diagnosis, treatment of the underlying aetiology if available and aggressive intensive care. Cerebral oedema, intracranial hypertension, metabolic derangements, bleeding and infection are common complications. The advent of liver transplantation has improved outcomes but mortality remains high despite medical advances.

KW - Coagulopathy

KW - Complication

KW - Encephalopathy

KW - Fulminant hepatitis

KW - Intensive care

KW - Mental status

UR - http://www.scopus.com/inward/record.url?scp=84888655064&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888655064&partnerID=8YFLogxK

U2 - 10.1002/9781444341294.ch5

DO - 10.1002/9781444341294.ch5

M3 - Chapter

AN - SCOPUS:84888655064

SN - 9781405134897

SP - 70

EP - 93

BT - Sherlock's Diseases of the Liver and Biliary System, 12th Edition

PB - Wiley-Blackwell

ER -

Acute Liver Failure

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this