Acute lung injury and the acute respiratory distress syndrome in the injured patient

Magdalena Bakowitz, Brandon Bruns, Maureen McCunn

Research output: Contribution to journalReview articlepeer-review

80 Scopus citations


Acute lung injury and acute respiratory distress syndrome are clinical entities of multi-factorial origin frequently seen in traumatically injured patients requiring intensive care. We performed an unsystematic search using PubMed and the Cochrane Database of Systematic Reviews up to January 2012. The purpose of this article is to review recent evidence for the pathophysiology and the management of acute lung injury/acute respiratory distress syndrome in the critically injured patient. Lung protective ventilation remains the most beneficial therapy. Future trials should compare intervention groups to controls receiving lung protective ventilation, and focus on relevant outcome measures such as duration of mechanical ventilation, length of intensive care unit stay, and mortality.

Original languageEnglish (US)
Article number54
JournalScandinavian Journal of Trauma, Resuscitation and Emergency Medicine
StatePublished - Aug 10 2012
Externally publishedYes


  • Acute lung injury (ALI)
  • Acute respiratory distress syndrome (ARDS)
  • Airway pressure release ventilation (APRV)
  • Extracorporeal membrane oxygenation (ECMO)
  • Flail chest
  • High-frequency oscillatory ventilation (HFOV)
  • Injury
  • Lung injury
  • Prone positioning
  • Rib open reduction internal fixation
  • Rib plating
  • Trauma

ASJC Scopus subject areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine


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