TY - JOUR
T1 - Acute management of optic neuritis
T2 - An evolving paradigm
AU - Horton, Lindsay
AU - Bennett, Jeffrey L.
N1 - Publisher Copyright:
© 2018 by North American Neuro-Ophthalmology Society.
PY - 2018
Y1 - 2018
N2 - The current management of acute optic neuritis (ON) is focused on expediting visual recovery through the use of high-dose intravenous corticosteroids. The recent identification of specific autoantibodies associated with central nervous system inflammatory disorders has provided novel insights into immune targets and mechanisms that impact the prognosis, treatment, and recurrence of ON. Therefore, neurologists and ophthalmologists need to be aware of clinical, laboratory, and imaging findings that may provide important clues to the etiology of ON and the potential need for aggressive management. Moving forward, rapid and accurate diagnosis of inflammatory ON will likely be critical for implementing clinical care that optimizes short-Term and long-Term therapeutic outcomes.
AB - The current management of acute optic neuritis (ON) is focused on expediting visual recovery through the use of high-dose intravenous corticosteroids. The recent identification of specific autoantibodies associated with central nervous system inflammatory disorders has provided novel insights into immune targets and mechanisms that impact the prognosis, treatment, and recurrence of ON. Therefore, neurologists and ophthalmologists need to be aware of clinical, laboratory, and imaging findings that may provide important clues to the etiology of ON and the potential need for aggressive management. Moving forward, rapid and accurate diagnosis of inflammatory ON will likely be critical for implementing clinical care that optimizes short-Term and long-Term therapeutic outcomes.
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U2 - 10.1097/WNO.0000000000000700
DO - 10.1097/WNO.0000000000000700
M3 - Article
C2 - 30106803
AN - SCOPUS:85056582110
SN - 1070-8022
VL - 38
SP - 358
EP - 367
JO - Journal of Neuro-Ophthalmology
JF - Journal of Neuro-Ophthalmology
IS - 3
ER -