Acute Myocardial Infarction in Sickle Cell Anemia

Chatchawin Assanasen, Reade A. Quinton, George R. Buchanan

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Cardiovascular dysfunction consistent with ischemia has been observed during episodes of painful crisis and following periods of heavy physical exertion in individuals with sickle cell disease. Similar findings have been observed in other individuals while taking the alpha-adrenergic agonist pseudoephedrine. However, acute myocardial infarction is extremely rare. The authors describe a case of sudden death in a child with sickle cell disease due to acute myocardial infarction and suggest that heavy exertional stress and use of pseudoephedrine may have precipitated the event.

Original languageEnglish (US)
Pages (from-to)978-981
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume25
Issue number12
DOIs
StatePublished - Dec 2003

Fingerprint

Pseudoephedrine
Sickle Cell Anemia
Myocardial Infarction
Adrenergic alpha-Agonists
Physical Exertion
Sudden Death
Ischemia

Keywords

  • Children
  • Exertional stress
  • Myocardial infarction
  • Pseudoephedrine
  • Sickle cell
  • Sudden death

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

Acute Myocardial Infarction in Sickle Cell Anemia. / Assanasen, Chatchawin; Quinton, Reade A.; Buchanan, George R.

In: Journal of Pediatric Hematology/Oncology, Vol. 25, No. 12, 12.2003, p. 978-981.

Research output: Contribution to journalArticle

Assanasen, Chatchawin ; Quinton, Reade A. ; Buchanan, George R. / Acute Myocardial Infarction in Sickle Cell Anemia. In: Journal of Pediatric Hematology/Oncology. 2003 ; Vol. 25, No. 12. pp. 978-981.
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