Acute pathological laughter

Darin T. Okuda, Abraham S C Chyung, Cynthia T. Chin, Emmanuelle Waubant

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Pseudobulbar effect is a condition characterized by uncontrollable episodes of inappropriate laughing or crying that are disproportionate and discordant to the situation at hand. We report on a 16-year-old woman presenting with acute pathological laughter in the context of CNS demyelinating disease. Brain MRI scans fortuitously obtained before and after the onset of this symptom demonstrated acute gadolinium-enhancing lesions in the cerebral peduncles. The etiology of this condition remains theoretical; however, the results here provide further insights into the pathways of emotional control.

Original languageEnglish (US)
Pages (from-to)1389-1390
Number of pages2
JournalMovement Disorders
Volume20
Issue number10
DOIs
StatePublished - Oct 2005

Fingerprint

Laughter
Crying
Central Nervous System Diseases
Gadolinium
Demyelinating Diseases
Hand
Magnetic Resonance Imaging
Brain
Cerebral Peduncle

Keywords

  • Inappropriate laughter
  • Multiple sclerosis
  • Pathological laughter
  • Pseudobulbar affect

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Okuda, D. T., Chyung, A. S. C., Chin, C. T., & Waubant, E. (2005). Acute pathological laughter. Movement Disorders, 20(10), 1389-1390. https://doi.org/10.1002/mds.20607

Acute pathological laughter. / Okuda, Darin T.; Chyung, Abraham S C; Chin, Cynthia T.; Waubant, Emmanuelle.

In: Movement Disorders, Vol. 20, No. 10, 10.2005, p. 1389-1390.

Research output: Contribution to journalArticle

Okuda, DT, Chyung, ASC, Chin, CT & Waubant, E 2005, 'Acute pathological laughter', Movement Disorders, vol. 20, no. 10, pp. 1389-1390. https://doi.org/10.1002/mds.20607
Okuda DT, Chyung ASC, Chin CT, Waubant E. Acute pathological laughter. Movement Disorders. 2005 Oct;20(10):1389-1390. https://doi.org/10.1002/mds.20607
Okuda, Darin T. ; Chyung, Abraham S C ; Chin, Cynthia T. ; Waubant, Emmanuelle. / Acute pathological laughter. In: Movement Disorders. 2005 ; Vol. 20, No. 10. pp. 1389-1390.
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