Ad interim recommendations for diagnosing SARS-CoV-2 infection by the IFCC SARS-CoV-2 variants working group

Giuseppe Lippi, Julien Favresse, Michael M. Gromiha, Jeffrey A. Sorelle, Mario Plebani, Brandon M. Henry

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

This document, endorsed by the IFCC Working Group on SARS-CoV-2 Variants, aims to update previous indications for diagnosing acute SARS-CoV-2 infection, taking into consideration the evidence that has emerged after the origin and spread of new lineages and sub-lineages of the virus characterized by mutated genetics and altered biochemical, biological and clinical characteristics. These indications encompass the use of different diagnostic strategies in specific clinical settings, such as high risk of SARS-CoV-2 infection (symptomatic patients), low risk of SARS-CoV-2 infection (asymptomatic subjects) at hospital admission/contact tracing, testing in asymptomatic subjects, in epidemiologic surveys and/or population screening, along with tentative indications for identification of new lineages and/or sub-lineages of SARS-CoV-2.

Original languageEnglish (US)
Pages (from-to)975-981
Number of pages7
JournalClinical Chemistry and Laboratory Medicine
Volume60
Issue number7
DOIs
StatePublished - Jun 1 2022
Externally publishedYes

Keywords

  • COVID-19
  • SARS-CoV-2
  • diagnosis
  • sequencing
  • variants

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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