Adaptive control of induced hypotension with optimum drug infusion

Khosrow Behbehani, Russell J. Cross, Kevin Klein

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The authors describe an adaptive control strategy that is suited for automatic control of mean arterial blood pressure (MABP). The performance of the control was evaluated for application of sodium nitroprusside, a vasodilator drug, using a computer simulation with a model of the patient response derived from actual patient data. One feature of the controller is its ability to optimize the quantity of infused drug without generating an offset in the controlled pressure. A comparison with another control strategy which has been used in the clinics is presented. The proposed controller appears to be excellent in regulating MABP.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual Conference on Engineering in Medicine and Biology
Place of PublicationPiscataway, NJ, United States
PublisherPubl by IEEE
Pages934-935
Number of pages2
Editionpt 3
ISBN (Print)0879425598
Publication statusPublished - 1990
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: Nov 1 1990Nov 4 1990

Other

OtherProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA
Period11/1/9011/4/90

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ASJC Scopus subject areas

  • Bioengineering

Cite this

Behbehani, K., Cross, R. J., & Klein, K. (1990). Adaptive control of induced hypotension with optimum drug infusion. In Proceedings of the Annual Conference on Engineering in Medicine and Biology (pt 3 ed., pp. 934-935). Piscataway, NJ, United States: Publ by IEEE.