Adiabatic JHSQC for 13C isotopomer analysis

Matthew E. Merritt, Shawn C. Burgess, Timothy D. Spitzer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A previous implementation of JHSQC enhanced the detection limits for 13C isotopomer analysis, but owing to experimental instabilities required extensive calibration prior to data collection. The addition of adiabatic pulses as well as a double spin-echo during the heteronuclear transfer periods has dramatically increased the precision of the experiment and done away with the need for calibration prior to running each sample. This new experiment allows the sensitivity gains from inverse detection to be realized in a time-efficient manner for the experimentalist.

Original languageEnglish (US)
Pages (from-to)463-466
Number of pages4
JournalMagnetic Resonance in Chemistry
Volume44
Issue number4
DOIs
StatePublished - Apr 2006

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Calibration
echoes
Experiments
sensitivity
pulses

Keywords

  • Adiabatic pulses
  • HSQC
  • Isotopomer analysis
  • NMR
  • Stable isotopes

ASJC Scopus subject areas

  • Chemistry(all)
  • Physical and Theoretical Chemistry
  • Spectroscopy

Cite this

Adiabatic JHSQC for 13C isotopomer analysis. / Merritt, Matthew E.; Burgess, Shawn C.; Spitzer, Timothy D.

In: Magnetic Resonance in Chemistry, Vol. 44, No. 4, 04.2006, p. 463-466.

Research output: Contribution to journalArticle

Merritt, Matthew E. ; Burgess, Shawn C. ; Spitzer, Timothy D. / Adiabatic JHSQC for 13C isotopomer analysis. In: Magnetic Resonance in Chemistry. 2006 ; Vol. 44, No. 4. pp. 463-466.
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