Abstract
Appearance of local fibrotic structures around and beneath hair follicles during their involution is a known hallmark of androgenetic alopecia (AGA). We hypothesise that this fibrosis can be connected with recently uncovered adipocyte-myofibroblast transition (AMT) involving the dermal adipocytes. This reflects that AMT is at least partially androgen-dependent, and we propose that AMT may play a role in AGA.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 522-523 |
| Number of pages | 2 |
| Journal | Experimental Dermatology |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2017 |
Keywords
- adipocyte-myofibroblast transition
- androgenetic alopecia
- perifollicular fibrosis
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Dermatology
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Cite this
Kruglikov, I. L., & Scherer, P. E. (2017). Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia. Experimental Dermatology, 26(6), 522-523. https://doi.org/10.1111/exd.13379