Adjuvant chemotherapy for treatment of unresectable and metastatic angiomatoid malignant fibrous histiocytoma

J. C. Bernini, D. W. Fort, M. Pritchard, B. B. Rogers, N. J. Winick

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Angiomatoid malignant fibrous histiocytoma (AMFH) is a low grade soft tissue sarcoma usually treated with surgery alone. Only one adult patient has been treated with systemic chemotherapy. The authors report a case of unresectable, metastatic AMFH treated initially with vincristine, doxorubicin, dactinomycin, and cyclophosphamide. A complete response at the metastatic site and a marked reduction in the size of the primary tumor allowed complete surgical excision 7 months after treatment was initiated. The patient remains disease free 19 months after being diagnosed. It was concluded that systemic chemotherapy may be effective in patients with AMFH.

Original languageEnglish (US)
Pages (from-to)962-964
Number of pages3
JournalCancer
Volume74
Issue number3
DOIs
StatePublished - Aug 1 1994

Keywords

  • angiomatoid malignant fibrous histiocytoma
  • children
  • malignant fibrous histiocytoma
  • sarcoma

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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