Adrenocortical blastoma

Kyle Molberg, Frank Vuttch, David Stewart, Jorge Albores-Saavedra

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only mvimentin reactivity. We propose the term "adrenocortical blastoma" for this unusual neoplasm.

Original languageEnglish (US)
Pages (from-to)1187-1190
Number of pages4
JournalHuman Pathology
Volume23
Issue number10
DOIs
StatePublished - 1992

Fingerprint

Neoplasms
Adrenal Cortex
Coloring Agents
Epithelial Cells
Serum

Keywords

  • adrenocortical blastoma
  • adrenocortical carcinoma
  • adrenocortical embryology
  • pediatric adrenocortical tumors

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Molberg, K., Vuttch, F., Stewart, D., & Albores-Saavedra, J. (1992). Adrenocortical blastoma. Human Pathology, 23(10), 1187-1190. https://doi.org/10.1016/0046-8177(92)90040-A

Adrenocortical blastoma. / Molberg, Kyle; Vuttch, Frank; Stewart, David; Albores-Saavedra, Jorge.

In: Human Pathology, Vol. 23, No. 10, 1992, p. 1187-1190.

Research output: Contribution to journalArticle

Molberg, K, Vuttch, F, Stewart, D & Albores-Saavedra, J 1992, 'Adrenocortical blastoma', Human Pathology, vol. 23, no. 10, pp. 1187-1190. https://doi.org/10.1016/0046-8177(92)90040-A
Molberg K, Vuttch F, Stewart D, Albores-Saavedra J. Adrenocortical blastoma. Human Pathology. 1992;23(10):1187-1190. https://doi.org/10.1016/0046-8177(92)90040-A
Molberg, Kyle ; Vuttch, Frank ; Stewart, David ; Albores-Saavedra, Jorge. / Adrenocortical blastoma. In: Human Pathology. 1992 ; Vol. 23, No. 10. pp. 1187-1190.
@article{13c60cf275d2445e8ffa0c64e3296821,
title = "Adrenocortical blastoma",
abstract = "We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only mvimentin reactivity. We propose the term {"}adrenocortical blastoma{"} for this unusual neoplasm.",
keywords = "adrenocortical blastoma, adrenocortical carcinoma, adrenocortical embryology, pediatric adrenocortical tumors",
author = "Kyle Molberg and Frank Vuttch and David Stewart and Jorge Albores-Saavedra",
year = "1992",
doi = "10.1016/0046-8177(92)90040-A",
language = "English (US)",
volume = "23",
pages = "1187--1190",
journal = "Human Pathology",
issn = "0046-8177",
publisher = "W.B. Saunders Ltd",
number = "10",

}

TY - JOUR

T1 - Adrenocortical blastoma

AU - Molberg, Kyle

AU - Vuttch, Frank

AU - Stewart, David

AU - Albores-Saavedra, Jorge

PY - 1992

Y1 - 1992

N2 - We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only mvimentin reactivity. We propose the term "adrenocortical blastoma" for this unusual neoplasm.

AB - We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only mvimentin reactivity. We propose the term "adrenocortical blastoma" for this unusual neoplasm.

KW - adrenocortical blastoma

KW - adrenocortical carcinoma

KW - adrenocortical embryology

KW - pediatric adrenocortical tumors

UR - http://www.scopus.com/inward/record.url?scp=0026770186&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026770186&partnerID=8YFLogxK

U2 - 10.1016/0046-8177(92)90040-A

DO - 10.1016/0046-8177(92)90040-A

M3 - Article

C2 - 1398649

AN - SCOPUS:0026770186

VL - 23

SP - 1187

EP - 1190

JO - Human Pathology

JF - Human Pathology

SN - 0046-8177

IS - 10

ER -