Adrenocortical blastoma

Kyle Molberg, Frank Vuttch, David Stewart, Jorge Albores-Saavedra

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only mvimentin reactivity. We propose the term "adrenocortical blastoma" for this unusual neoplasm.

Original languageEnglish (US)
Pages (from-to)1187-1190
Number of pages4
JournalHuman Pathology
Volume23
Issue number10
DOIs
StatePublished - Oct 1992

Keywords

  • adrenocortical blastoma
  • adrenocortical carcinoma
  • adrenocortical embryology
  • pediatric adrenocortical tumors

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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    Molberg, K., Vuttch, F., Stewart, D., & Albores-Saavedra, J. (1992). Adrenocortical blastoma. Human Pathology, 23(10), 1187-1190. https://doi.org/10.1016/0046-8177(92)90040-A