Adult lymphoblastic lymphoma: High incidence of central nervous system relapse in patients treated with the stanford university protocol

J. W. Sweetenham, G. M. Mead, J. M.A. Whitehouse

Research output: Contribution to journalArticle

9 Scopus citations


Twelve adult patients with non-leukaemic lymphoblastic lymphoma were treated with combination chemotherapy and central nervous system prophylaxis according to the protocol developed at Stanford University. Despite strict adherence to the Stanford protocol, 4 of 12 patients relapsed in the CNS, all with meningeal disease. Only four of the 12 patients are in continuing complete remission 6 to 88 months from the completion of induction therapy. These results are inferior to those previously reported for this regimen, and fail to confirm the high rate of control of CNS disease.

Original languageEnglish (US)
Pages (from-to)839-841
Number of pages3
JournalAnnals of Oncology
Issue number10
Publication statusPublished - Dec 1 1992
Externally publishedYes



  • Chemotherapy
  • CNS
  • Lymphoblastic lymphoma
  • Relapse

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this