Adult primary peripheral PNET/Ewing’s sarcoma of the cervical and thoracic spine

Raamis Khwaja, Emmanuel Mantilla, Karen Fink, Edward Pan

Research output: Contribution to journalArticle

Abstract

This case report describes a patient with a rare occurrence of primary spinal intramedullary Ewing’s sarcoma (ES) in the cervical and thoracic spine. The older age of disease occurrence, uncommon location in the cervical and thoracic spine, and EWSR1 gene fusion as the basis of diagnosis are unique features of this case. There is no clear protocol for treatment of primary extraskeletal ES of the spine, with controversy between evidence for pursuing surgery versus a combination of radiation and chemotherapy. Our patient was treated with temozolomide chemotherapy for recurrent metastatic disease of primary ES of the spine.

Original languageEnglish (US)
Pages (from-to)4463-4465
Number of pages3
JournalAnticancer Research
Volume39
Issue number8
DOIs
StatePublished - Jan 1 2019

Keywords

  • Chemotherapy
  • CNS
  • Ewing’s Sarcoma
  • Gene fusion
  • Immunohistochemistry
  • Primitive neuroectodermal tumor
  • Spinal

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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