Advanced Glycation End Products and Risks for Chronic Diseases: Intervening Through Lifestyle Modification

Chandan Prasad, Kathleen E Davis, Victorine Imrhan, Shanil Juma, Parakat Vijayagopal

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Advanced glycation end products (AGEs) are a family of compounds of diverse chemical nature that are the products of nonenzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. AGEs bind to one or more of their multiple receptors (RAGE) found on a variety of cell types and elicit an array of biologic responses. In this review, we have summarized the data on the nature of AGEs and issues associated with their measurements, their receptors, and changes in their expression under different physiologic and disease states. Last, we have used this information to prescribe lifestyle choices to modulate AGE-RAGE cycle for better health.

Original languageEnglish (US)
Pages (from-to)384-404
Number of pages21
JournalAmerican Journal of Lifestyle Medicine
Volume13
Issue number4
DOIs
StatePublished - Jul 1 2019

Fingerprint

Advanced Glycosylation End Products
Nucleic Acids
Life Style
Chronic Disease
Lipids
Health
Proteins

Keywords

  • advanced glycation end products
  • AGEs
  • diet
  • inflammation
  • lifestyle

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Advanced Glycation End Products and Risks for Chronic Diseases : Intervening Through Lifestyle Modification. / Prasad, Chandan; Davis, Kathleen E; Imrhan, Victorine; Juma, Shanil; Vijayagopal, Parakat.

In: American Journal of Lifestyle Medicine, Vol. 13, No. 4, 01.07.2019, p. 384-404.

Research output: Contribution to journalReview article

Prasad, Chandan ; Davis, Kathleen E ; Imrhan, Victorine ; Juma, Shanil ; Vijayagopal, Parakat. / Advanced Glycation End Products and Risks for Chronic Diseases : Intervening Through Lifestyle Modification. In: American Journal of Lifestyle Medicine. 2019 ; Vol. 13, No. 4. pp. 384-404.
@article{4b7c146de7cc484cbef4d06c815c36e5,
title = "Advanced Glycation End Products and Risks for Chronic Diseases: Intervening Through Lifestyle Modification",
abstract = "Advanced glycation end products (AGEs) are a family of compounds of diverse chemical nature that are the products of nonenzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. AGEs bind to one or more of their multiple receptors (RAGE) found on a variety of cell types and elicit an array of biologic responses. In this review, we have summarized the data on the nature of AGEs and issues associated with their measurements, their receptors, and changes in their expression under different physiologic and disease states. Last, we have used this information to prescribe lifestyle choices to modulate AGE-RAGE cycle for better health.",
keywords = "advanced glycation end products, AGEs, diet, inflammation, lifestyle",
author = "Chandan Prasad and Davis, {Kathleen E} and Victorine Imrhan and Shanil Juma and Parakat Vijayagopal",
year = "2019",
month = "7",
day = "1",
doi = "10.1177/1559827617708991",
language = "English (US)",
volume = "13",
pages = "384--404",
journal = "American Journal of Lifestyle Medicine",
issn = "1559-8276",
publisher = "SAGE Publications Inc.",
number = "4",

}

TY - JOUR

T1 - Advanced Glycation End Products and Risks for Chronic Diseases

T2 - Intervening Through Lifestyle Modification

AU - Prasad, Chandan

AU - Davis, Kathleen E

AU - Imrhan, Victorine

AU - Juma, Shanil

AU - Vijayagopal, Parakat

PY - 2019/7/1

Y1 - 2019/7/1

N2 - Advanced glycation end products (AGEs) are a family of compounds of diverse chemical nature that are the products of nonenzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. AGEs bind to one or more of their multiple receptors (RAGE) found on a variety of cell types and elicit an array of biologic responses. In this review, we have summarized the data on the nature of AGEs and issues associated with their measurements, their receptors, and changes in their expression under different physiologic and disease states. Last, we have used this information to prescribe lifestyle choices to modulate AGE-RAGE cycle for better health.

AB - Advanced glycation end products (AGEs) are a family of compounds of diverse chemical nature that are the products of nonenzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. AGEs bind to one or more of their multiple receptors (RAGE) found on a variety of cell types and elicit an array of biologic responses. In this review, we have summarized the data on the nature of AGEs and issues associated with their measurements, their receptors, and changes in their expression under different physiologic and disease states. Last, we have used this information to prescribe lifestyle choices to modulate AGE-RAGE cycle for better health.

KW - advanced glycation end products

KW - AGEs

KW - diet

KW - inflammation

KW - lifestyle

UR - http://www.scopus.com/inward/record.url?scp=85041488274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041488274&partnerID=8YFLogxK

U2 - 10.1177/1559827617708991

DO - 10.1177/1559827617708991

M3 - Review article

C2 - 31285723

AN - SCOPUS:85041488274

VL - 13

SP - 384

EP - 404

JO - American Journal of Lifestyle Medicine

JF - American Journal of Lifestyle Medicine

SN - 1559-8276

IS - 4

ER -