Advanced Neuroimaging Techniques for Central Neuromodulation

Angela Downes, Nader Pouratian

Research output: Contribution to journalReview articlepeer-review

Abstract

Deep brain stimulation an effective treatment of many neurologic conditions such as Parkinson disease, essential tremor, dystonia, and obsessive-compulsive disorder. Structural and functional neuroimaging studies provide the opportunity to visualize the dysfunctional nodes and networks underlying neurologic and psychiatric disease, and to thereby realize new targets for neuromodulation as well as personalize current therapy. This article reviews contemporary advances in neuroimaging in the basic sciences and how they can be applied to redirect and propel functional neurosurgery toward a goal of functional localization of targets with individualized maps and identification of novel targets for other neuropsychiatric diseases.

Original languageEnglish (US)
Pages (from-to)173-185
Number of pages13
JournalNeurosurgery clinics of North America
Volume25
Issue number1
DOIs
StatePublished - Jan 2014
Externally publishedYes

Keywords

  • 7T MRI
  • Brain mapping
  • Deep brain stimulation (DBS)
  • DTI
  • FMRI
  • Functional imaging

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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