Advances in the diagnosis and medical management of cushing’s syndrome

Danae A. Delivanis, Anu Sharma, Oksana Hamidi, Meera Shah, Irina Bancos

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The clinical constellation of signs and symptoms consistent with glucocorticoid excess is termed Cushing syndrome (CS). The most common etiology for CS is the administration of exogenous glucocorticoids. This chapter will focus on endogenous forms of overt cortisol excess. Patients with CS present with a spectrum of clinical manifestations ranging from metabolic abnormalities to classical features of CS. Clinical presentation depends on the severity and duration of cortisol excess, and individual susceptibility. CS presents with high morbidity and mortality, especially if unrecognized or diagnosis is delayed. This chapter will describe epidemiology, diagnostic workup, clinical presentation, and management of various types of endogenous CS.

Original languageEnglish (US)
Title of host publicationAdvances in Treatment and Management in Surgical Endocrinology
PublisherElsevier
Pages151-174
Number of pages24
ISBN (Electronic)9780323661959
ISBN (Print)9780323661942
DOIs
StatePublished - Jan 1 2019

Keywords

  • Adrenalectomy
  • Cortisol
  • Cushing syndrome
  • Diagnosis
  • Ectopic cushing syndrome
  • Pituitary cushing disease
  • Therapy

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Advances in the diagnosis and medical management of cushing’s syndrome'. Together they form a unique fingerprint.

Cite this