Advances in the management of hypothermia

L. M. Gentilello

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Many believe that the consequence of hypothermia is an orderly decrease in metabolism. However, oxygen consumption is increased, except when anesthetics and neuromuscular blocking agents are used to block the thermoregulatory response. This may be detrimental in patients with a bleeding diathesis as a result of the impairment of platelet function, activation of the fibrinolytic cascade, and inhibition of clotting enzyme kinetics that are associated with cooling of the blood. To date, a potential benefit of hypothermia in trauma patients has not been identified. Based on current data, every attempt should be made to prevent heat loss from occurring and to aggressively treat hypothermia once it has occurred.

Original languageEnglish (US)
Pages (from-to)243-256
Number of pages14
JournalSurgical Clinics of North America
Volume75
Issue number2
StatePublished - 1995

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Hypothermia
Neuromuscular Blocking Agents
Disease Susceptibility
Platelet Activation
Oxygen Consumption
Anesthetics
Hot Temperature
Hemorrhage
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery

Cite this

Advances in the management of hypothermia. / Gentilello, L. M.

In: Surgical Clinics of North America, Vol. 75, No. 2, 1995, p. 243-256.

Research output: Contribution to journalArticle

Gentilello, LM 1995, 'Advances in the management of hypothermia', Surgical Clinics of North America, vol. 75, no. 2, pp. 243-256.
Gentilello, L. M. / Advances in the management of hypothermia. In: Surgical Clinics of North America. 1995 ; Vol. 75, No. 2. pp. 243-256.
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