African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol

Thomas E. Goodwin; Felisia D. Brown; Richard W. Counts; Nichole C. Dowdy; Patrick L. Fraley; Randall A. Hughes; Daniel Z. Liu; Courtney D. Mashburn; Josh D. Rankin; Russell S. Roberson; Katie D. Wooley; Elizabeth L. Rasmussen; Scott W. Riddle; Heidi S. Riddle; Stefan Schulz

doi:10.1021/np010647c

African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol

Thomas E. Goodwin, Felisia D. Brown, Richard W. Counts, Nichole C. Dowdy, Patrick L. Fraley, Randall A. Hughes, Daniel Z. Liu, Courtney D. Mashburn, Josh D. Rankin, Russell S. Roberson, Katie D. Wooley, Elizabeth L. Rasmussen, Scott W. Riddle, Heidi S. Riddle, Stefan Schulz

Anesthesiology & Pain Management

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

A search for potential semiochemicals revealed nerolidol (6), albicanol (7), and the new 2,3-dihydrofarnesol derivatives 8-10 in the temporal gland secretions of African elephants. A novel synthesis from (E,E)-farnesol (1) provided compounds 8-10 for GC-MS comparison to the natural products. This study confirms the farnesol family as frequently occurring secondary metabolites in African elephant temporal gland secretions.

Original language	English (US)
Pages (from-to)	1319-1322
Number of pages	4
Journal	Journal of Natural Products
Volume	65
Issue number	9
DOIs	https://doi.org/10.1021/np010647c
State	Published - Sep 1 2002

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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Goodwin, T. E., Brown, F. D., Counts, R. W., Dowdy, N. C., Fraley, P. L., Hughes, R. A., Liu, D. Z., Mashburn, C. D., Rankin, J. D., Roberson, R. S., Wooley, K. D., Rasmussen, E. L., Riddle, S. W., Riddle, H. S., & Schulz, S. (2002). African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol. Journal of Natural Products, 65(9), 1319-1322. https://doi.org/10.1021/np010647c

Goodwin, TE, Brown, FD, Counts, RW, Dowdy, NC, Fraley, PL, Hughes, RA, Liu, DZ, Mashburn, CD, Rankin, JD, Roberson, RS, Wooley, KD, Rasmussen, EL, Riddle, SW, Riddle, HS & Schulz, S 2002, 'African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol', Journal of Natural Products, vol. 65, no. 9, pp. 1319-1322. https://doi.org/10.1021/np010647c

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abstract = "A search for potential semiochemicals revealed nerolidol (6), albicanol (7), and the new 2,3-dihydrofarnesol derivatives 8-10 in the temporal gland secretions of African elephants. A novel synthesis from (E,E)-farnesol (1) provided compounds 8-10 for GC-MS comparison to the natural products. This study confirms the farnesol family as frequently occurring secondary metabolites in African elephant temporal gland secretions.",

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AU - Fraley, Patrick L.

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AU - Roberson, Russell S.

AU - Wooley, Katie D.

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AU - Schulz, Stefan

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African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol

Abstract

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