Abstract
Background: Many patients with spinal juvenile pilocytic astrocytoma can experience prolonged remission after resection. However, some reports suggest that pregnancy may be associated with progression. Case Description: The authors provide an image report highlighting a case of rapid and aggressive transformation of an intramedullary astrocytoma of the cervical spine in a pregnant patient. Over the course of 1 year, the lesion progressed from a juvenile pilocytic astrocytoma to an anaplastic astrocytoma. Genetic testing revealed mutations associated with aggressive behavior. Conclusion: The case and associated imaging demonstrate the importance of close neurologic monitoring and counseling regarding risk of progression in pregnant patients with spinal gliomas.
Original language | English (US) |
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Article number | 466 |
Journal | Surgical Neurology International |
Volume | 12 |
DOIs | |
State | Published - 2021 |
Keywords
- Anaplastic astrocytoma
- FGFR1
- Intramedullary
- Pilocytic astrocytoma
- SETD2
- TACC1
ASJC Scopus subject areas
- Surgery
- Clinical Neurology