ALBUMIN UPTAKE ON C//1//8 ALKYLATED POLYURETHANE FOAM.

L. King-Breeding, M. S. Munro, R. C. Eberhart

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have shown that C//1//8 alkylation of polyurethane sheets and tubes selectively increases the affinities of these materials for albumin, in vitro and in vivo. We have also demonstrated a correlation between the enhancement of albumin affinity by this process and improved thromboresistance. In this study we extend the alkylation technique to open cell polyurethane foams of high porosity and pore size, such as are used in blood filtration devices. We report the enhancement of the albumin affinity of these materials by this technique, both with and without Antifoam A pretreatment.

Original languageEnglish (US)
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
EditorsJames M. Anderson
Place of PublicationSan Antonio, TX, USA
PublisherSoc for Biomaterials
Pages303
Number of pages1
Volume7
StatePublished - 1984

ASJC Scopus subject areas

  • Materials Science(all)

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    King-Breeding, L., Munro, M. S., & Eberhart, R. C. (1984). ALBUMIN UPTAKE ON C//1//8 ALKYLATED POLYURETHANE FOAM. In J. M. Anderson (Ed.), Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium (Vol. 7, pp. 303). Soc for Biomaterials.