Alcohol-induced liver disease

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Hepatic changes resulting from the regular ingestion of alcohol are many and include fat infiltration, alcoholic hepatitis, and cirrhosis. Only 10% to 15% of chronic alcoholics develop liver disease. Women are more susceptible. An area of considerable importance is the high prevalence of concomitant infection with hepatitis C virus in chronic alcoholics. Patients who have hepatitis C and alcohol-induced liver injury are much more likely to develop progressive liver disease and cirrhosis. Corticosteroid therapy has proven useful in the treatment of patients with severe acute alcoholic hepatitis.

Original languageEnglish (US)
Pages (from-to)115-131
Number of pages17
JournalClinics in Liver Disease
Volume4
Issue number1
StatePublished - 2000

Fingerprint

Alcoholic Hepatitis
Liver Diseases
Alcohols
Alcoholic Liver Cirrhosis
Alcoholic Liver Diseases
Liver
Alcoholics
Hepatitis C
Hepacivirus
Liver Cirrhosis
Adrenal Cortex Hormones
Eating
Fats
Wounds and Injuries
Therapeutics
Infection

ASJC Scopus subject areas

  • Hepatology

Cite this

Alcohol-induced liver disease. / Maddrey, W. C.

In: Clinics in Liver Disease, Vol. 4, No. 1, 2000, p. 115-131.

Research output: Contribution to journalArticle

Maddrey, W. C. / Alcohol-induced liver disease. In: Clinics in Liver Disease. 2000 ; Vol. 4, No. 1. pp. 115-131.
@article{174f871c9d8940449483cbf7136cb160,
title = "Alcohol-induced liver disease",
abstract = "Hepatic changes resulting from the regular ingestion of alcohol are many and include fat infiltration, alcoholic hepatitis, and cirrhosis. Only 10{\%} to 15{\%} of chronic alcoholics develop liver disease. Women are more susceptible. An area of considerable importance is the high prevalence of concomitant infection with hepatitis C virus in chronic alcoholics. Patients who have hepatitis C and alcohol-induced liver injury are much more likely to develop progressive liver disease and cirrhosis. Corticosteroid therapy has proven useful in the treatment of patients with severe acute alcoholic hepatitis.",
author = "Maddrey, {W. C.}",
year = "2000",
language = "English (US)",
volume = "4",
pages = "115--131",
journal = "Clinics in Liver Disease",
issn = "1089-3261",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Alcohol-induced liver disease

AU - Maddrey, W. C.

PY - 2000

Y1 - 2000

N2 - Hepatic changes resulting from the regular ingestion of alcohol are many and include fat infiltration, alcoholic hepatitis, and cirrhosis. Only 10% to 15% of chronic alcoholics develop liver disease. Women are more susceptible. An area of considerable importance is the high prevalence of concomitant infection with hepatitis C virus in chronic alcoholics. Patients who have hepatitis C and alcohol-induced liver injury are much more likely to develop progressive liver disease and cirrhosis. Corticosteroid therapy has proven useful in the treatment of patients with severe acute alcoholic hepatitis.

AB - Hepatic changes resulting from the regular ingestion of alcohol are many and include fat infiltration, alcoholic hepatitis, and cirrhosis. Only 10% to 15% of chronic alcoholics develop liver disease. Women are more susceptible. An area of considerable importance is the high prevalence of concomitant infection with hepatitis C virus in chronic alcoholics. Patients who have hepatitis C and alcohol-induced liver injury are much more likely to develop progressive liver disease and cirrhosis. Corticosteroid therapy has proven useful in the treatment of patients with severe acute alcoholic hepatitis.

UR - http://www.scopus.com/inward/record.url?scp=0034424754&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034424754&partnerID=8YFLogxK

M3 - Article

VL - 4

SP - 115

EP - 131

JO - Clinics in Liver Disease

JF - Clinics in Liver Disease

SN - 1089-3261

IS - 1

ER -