Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Peter G. Passias; Cole Bortz; Haddy Alas; Frank A. Segreto; Samantha R. Horn; Yael U. Ihejirika; Dennis Vasquez-Montes; Katherine E. Pierce; Avery E. Brown; Kartik Shenoy; Edward M. DelSole; Bradley Johnson; Cheongeun Oh; Peter L. Zhou; Chloe Deflorimonte; Ekhamjeet S. Dhillon; Pawel P. Jankowski; Bassel G. Diebo; Virginie Lafage; Renaud Lafage; Shaleen N. Vira; John A. Bendo; Jeffrey A. Goldstein; Frank J. Schwab; Michael C. Gerling

doi:10.1016/j.jor.2018.12.011

Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Peter G. Passias, Cole Bortz, Haddy Alas, Frank A. Segreto, Samantha R. Horn, Yael U. Ihejirika, Dennis Vasquez-Montes, Katherine E. Pierce, Avery E. Brown, Kartik Shenoy, Edward M. DelSole, Bradley Johnson, Cheongeun Oh, Peter L. Zhou, Chloe Deflorimonte, Ekhamjeet S. Dhillon, Pawel P. Jankowski, Bassel G. Diebo, Virginie Lafage, Renaud LafageShaleen N. Vira, John A. Bendo, Jeffrey A. Goldstein, Frank J. Schwab, Michael C. Gerling

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

Original language	English (US)
Pages (from-to)	36-40
Number of pages	5
Journal	Journal of Orthopaedics
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/j.jor.2018.12.011
State	Published - Jan 1 2019
Externally published	Yes

Keywords

30-Day complication rates
Alcoholism
Predictors
Primary spine fusion
Pseudarthrosis
Surgical revision

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.jor.2018.12.011

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Passias, P. G., Bortz, C., Alas, H., Segreto, F. A., Horn, S. R., Ihejirika, Y. U., Vasquez-Montes, D., Pierce, K. E., Brown, A. E., Shenoy, K., DelSole, E. M., Johnson, B., Oh, C., Zhou, P. L., Deflorimonte, C., Dhillon, E. S., Jankowski, P. P., Diebo, B. G., Lafage, V., ... Gerling, M. C. (2019). Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013. Journal of Orthopaedics, 16(1), 36-40. https://doi.org/10.1016/j.jor.2018.12.011

Passias, PG, Bortz, C, Alas, H, Segreto, FA, Horn, SR, Ihejirika, YU, Vasquez-Montes, D, Pierce, KE, Brown, AE, Shenoy, K, DelSole, EM, Johnson, B, Oh, C, Zhou, PL, Deflorimonte, C, Dhillon, ES, Jankowski, PP, Diebo, BG, Lafage, V, Lafage, R, Vira, SN, Bendo, JA, Goldstein, JA, Schwab, FJ & Gerling, MC 2019, 'Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013', Journal of Orthopaedics, vol. 16, no. 1, pp. 36-40. https://doi.org/10.1016/j.jor.2018.12.011

@article{228c59599a38450b8bccf64add4aae88,

title = "Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013",

abstract = "Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.",

keywords = "30-Day complication rates, Alcoholism, Predictors, Primary spine fusion, Pseudarthrosis, Surgical revision",

author = "Passias, {Peter G.} and Cole Bortz and Haddy Alas and Segreto, {Frank A.} and Horn, {Samantha R.} and Ihejirika, {Yael U.} and Dennis Vasquez-Montes and Pierce, {Katherine E.} and Brown, {Avery E.} and Kartik Shenoy and DelSole, {Edward M.} and Bradley Johnson and Cheongeun Oh and Zhou, {Peter L.} and Chloe Deflorimonte and Dhillon, {Ekhamjeet S.} and Jankowski, {Pawel P.} and Diebo, {Bassel G.} and Virginie Lafage and Renaud Lafage and Vira, {Shaleen N.} and Bendo, {John A.} and Goldstein, {Jeffrey A.} and Schwab, {Frank J.} and Gerling, {Michael C.}",

note = "Publisher Copyright: {\textcopyright} 2018 Prof. PK Surendran Memorial Education Foundation",

year = "2019",

month = jan,

day = "1",

doi = "10.1016/j.jor.2018.12.011",

language = "English (US)",

volume = "16",

pages = "36--40",

journal = "Journal of Orthopaedics",

issn = "0972-978X",

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TY - JOUR

T1 - Alcoholism as a predictor for pseudarthrosis in primary spine fusion

T2 - An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

AU - Passias, Peter G.

AU - Bortz, Cole

AU - Alas, Haddy

AU - Segreto, Frank A.

AU - Horn, Samantha R.

AU - Ihejirika, Yael U.

AU - Vasquez-Montes, Dennis

AU - Pierce, Katherine E.

AU - Brown, Avery E.

AU - Shenoy, Kartik

AU - DelSole, Edward M.

AU - Johnson, Bradley

AU - Oh, Cheongeun

AU - Zhou, Peter L.

AU - Deflorimonte, Chloe

AU - Dhillon, Ekhamjeet S.

AU - Jankowski, Pawel P.

AU - Diebo, Bassel G.

AU - Lafage, Virginie

AU - Lafage, Renaud

AU - Vira, Shaleen N.

AU - Bendo, John A.

AU - Goldstein, Jeffrey A.

AU - Schwab, Frank J.

AU - Gerling, Michael C.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

AB - Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

KW - 30-Day complication rates

KW - Alcoholism

KW - Predictors

KW - Primary spine fusion

KW - Pseudarthrosis

KW - Surgical revision

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U2 - 10.1016/j.jor.2018.12.011

DO - 10.1016/j.jor.2018.12.011

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C2 - 30662235

AN - SCOPUS:85058789258

SN - 0972-978X

VL - 16

SP - 36

EP - 40

JO - Journal of Orthopaedics

JF - Journal of Orthopaedics

IS - 1

ER -

Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Abstract

Keywords

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