Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Peter G. Passias, Cole Bortz, Haddy Alas, Frank A. Segreto, Samantha R. Horn, Yael U. Ihejirika, Dennis Vasquez-Montes, Katherine E. Pierce, Avery E. Brown, Kartik Shenoy, Edward M. DelSole, Bradley Johnson, Cheongeun Oh, Peter L. Zhou, Chloe Deflorimonte, Ekhamjeet S. Dhillon, Pawel P. Jankowski, Bassel G. Diebo, Virginie Lafage, Renaud LafageShaleen N. Vira, John A. Bendo, Jeffrey A. Goldstein, Frank J. Schwab, Michael C. Gerling

Research output: Contribution to journalArticle

Abstract

Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

Original languageEnglish (US)
Pages (from-to)36-40
Number of pages5
JournalJournal of Orthopaedics
Volume16
Issue number1
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Keywords

  • 30-Day complication rates
  • Alcoholism
  • Predictors
  • Primary spine fusion
  • Pseudarthrosis
  • Surgical revision

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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    Passias, P. G., Bortz, C., Alas, H., Segreto, F. A., Horn, S. R., Ihejirika, Y. U., Vasquez-Montes, D., Pierce, K. E., Brown, A. E., Shenoy, K., DelSole, E. M., Johnson, B., Oh, C., Zhou, P. L., Deflorimonte, C., Dhillon, E. S., Jankowski, P. P., Diebo, B. G., Lafage, V., ... Gerling, M. C. (2019). Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013. Journal of Orthopaedics, 16(1), 36-40. https://doi.org/10.1016/j.jor.2018.12.011