TY - JOUR
T1 - Alemtuzumab (Campath-1H) Induction in a Pediatric Heart Transplant
T2 - Successful Outcome and Rationale for Its Use
AU - Das, Bibhuti
AU - Shoemaker, Lawrence
AU - Recto, Michael
AU - Austin, Erle
AU - Dowling, Robert
PY - 2008/2
Y1 - 2008/2
N2 - Despite increasing clinical experience in adult transplantation, induction therapy with alemtuzumab (Campath-1H) has rarely been reported in pediatric solid-organ transplants, and has been limited to kidneys, intestine and multi-visceral organs. Basic science research and clinical observations reported from the adult experience suggest potential benefits of alemtuzumab in pediatric organ recipients. We report successful induction therapy with alemtuzumab and steroid-free maintenance therapy for cardiac transplantation in a teenager, and discuss its merits in this patient.
AB - Despite increasing clinical experience in adult transplantation, induction therapy with alemtuzumab (Campath-1H) has rarely been reported in pediatric solid-organ transplants, and has been limited to kidneys, intestine and multi-visceral organs. Basic science research and clinical observations reported from the adult experience suggest potential benefits of alemtuzumab in pediatric organ recipients. We report successful induction therapy with alemtuzumab and steroid-free maintenance therapy for cardiac transplantation in a teenager, and discuss its merits in this patient.
UR - http://www.scopus.com/inward/record.url?scp=38949153071&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38949153071&partnerID=8YFLogxK
U2 - 10.1016/j.healun.2007.11.569
DO - 10.1016/j.healun.2007.11.569
M3 - Article
C2 - 18267235
AN - SCOPUS:38949153071
SN - 1053-2498
VL - 27
SP - 242
EP - 244
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
IS - 2
ER -