Allele-selective inhibition of mutant huntingtin by peptide nucleic acid-peptide conjugates, locked nucleic acid, and small interfering RNA

Medicine & Life Sciences

• locked nucleic acid 100%
• Peptide Nucleic Acids 96%
• Huntington Disease 72%
• Small Interfering RNA 54%
• Psychological Inhibition 52%
• Alleles 47%
• Peptides 41%
• Huntingtin Protein 31%
• Aptitude 14%
• Pathology 13%
• Messenger RNA 12%
• Proteins 7%
• Therapeutics 3%

Chemical Compounds

• Locked Nucleic Acid 96%
• Small Interfering RNA 89%
• Peptide Nucleic Acid 81%
• Anti Huntington 73%
• Peptide 37%
• Protein 26%
• Oligomer 25%
• Block Like Crystal 21%

Arts & Humanities

• Allele 78%
• Protein 51%
• Repeats 43%
• Oligomers 32%
• Polymorphism 30%
• Pathology 18%
• Therapeutics 16%