Allergic Fungal Rhinosinusitis

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Allergic fungal rhinosinusitis is a phenotype of chronic rhinosinusitis with nasal polyposis, characterized by type 1 hypersensitivity to fungi, eosinophilic mucin with fungal hyphae in sinus secretions, and propensity for mucocele formation and bone erosion. Although its differentiation from other forms of chronic polypoid rhinosinusitis with eosinophilic mucin is sometimes problematic, type 1 hypersensitivity is a component of the disease process. Medical and surgical management can be augmented by immunotherapy directed toward the patient's specific allergen sensitivities. The primary rationale for immunotherapy is to control the allergic diathesis that may be contributing to the patient's chronic sinus inflammation.

Original languageEnglish (US)
Pages (from-to)697-710
Number of pages14
JournalOtolaryngologic Clinics of North America
Volume44
Issue number3
DOIs
StatePublished - Jun 2011

Fingerprint

Immediate Hypersensitivity
Mucins
Immunotherapy
Mucocele
Hyphae
Disease Susceptibility
Nose
Osteogenesis
Allergens
Fungi
Inflammation
Phenotype

Keywords

  • Allergic fungal sinusitis
  • Allergic mucin
  • Eosinophilic mucin
  • Eosinophilic mucin rhinosinusitis
  • Immunotherapy
  • Nasal polyps

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Allergic Fungal Rhinosinusitis. / Ryan, Matthew W.

In: Otolaryngologic Clinics of North America, Vol. 44, No. 3, 06.2011, p. 697-710.

Research output: Contribution to journalArticle

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