Ammonia Excretion and Renal Glutaminase Activity During Administration of Strong Acid and Buffer Acid.

Donald W. Seldin; H. C. Teng; Floyd C. Rector

doi:10.3181/00379727-94-22947

Ammonia Excretion and Renal Glutaminase Activity During Administration of Strong Acid and Buffer Acid.

Donald W. Seldin, H. C. Teng, Floyd C. Rector

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Activation of renal glutaminase during administration of NH4C1 does not appear to result from pre-renal effects of the acid load, since physiologically equivalent loads of NaH2P04 produced the same slight depression of serum bicarbonate but affected neither excretion of ammonia nor activity of renal glutaminase. Rather, it appears that activation of glutaminase is related to changes, as yet unidentified, within the kidney.

Original language	English (US)
Pages (from-to)	366-368
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	94
Issue number	2
DOIs	https://doi.org/10.3181/00379727-94-22947
State	Published - Feb 1957

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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title = "Ammonia Excretion and Renal Glutaminase Activity During Administration of Strong Acid and Buffer Acid.",

abstract = "Activation of renal glutaminase during administration of NH4C1 does not appear to result from pre-renal effects of the acid load, since physiologically equivalent loads of NaH2P04 produced the same slight depression of serum bicarbonate but affected neither excretion of ammonia nor activity of renal glutaminase. Rather, it appears that activation of glutaminase is related to changes, as yet unidentified, within the kidney.",

author = "Seldin, {Donald W.} and Teng, {H. C.} and Rector, {Floyd C.}",

note = "Funding Information: This investigation was supported by research grants from N.I.H., Public Health Service, and by Dallas Heart Assn. 2 1957 94 2 366 368 ",

year = "1957",

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AU - Seldin, Donald W.

AU - Teng, H. C.

AU - Rector, Floyd C.

N1 - Funding Information: This investigation was supported by research grants from N.I.H., Public Health Service, and by Dallas Heart Assn. 2 1957 94 2 366 368

PY - 1957/2

Y1 - 1957/2

N2 - Activation of renal glutaminase during administration of NH4C1 does not appear to result from pre-renal effects of the acid load, since physiologically equivalent loads of NaH2P04 produced the same slight depression of serum bicarbonate but affected neither excretion of ammonia nor activity of renal glutaminase. Rather, it appears that activation of glutaminase is related to changes, as yet unidentified, within the kidney.

AB - Activation of renal glutaminase during administration of NH4C1 does not appear to result from pre-renal effects of the acid load, since physiologically equivalent loads of NaH2P04 produced the same slight depression of serum bicarbonate but affected neither excretion of ammonia nor activity of renal glutaminase. Rather, it appears that activation of glutaminase is related to changes, as yet unidentified, within the kidney.

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JO - Proceedings of the Society for Experimental Biology and Medicine

JF - Proceedings of the Society for Experimental Biology and Medicine

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Ammonia Excretion and Renal Glutaminase Activity During Administration of Strong Acid and Buffer Acid.

Abstract

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