Amniotic fluid index and birth weight: Is there a relationship in diabetics with poor glycemic control?

Joy Y. Vink, Sarah H. Poggi, Alessandro Ghidini, Catherine Y. Spong

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Objective: This study was undertaken to evaluate if the previously demonstrated relationship between macrosomia (>4000 g) and polyhydramnios (>25 cm) is linear across birth weights (BW) in diabetic patients with poor glycemic control. Study design: Using a prospectively collected database of patients undergoing amniocentesis for fetal lung maturity for various indications with amniotic fluid index (AFI) obtained ≤7 days before delivery and BWs available (n = 69), we computed gestational age (GA) specific AFI and BW centiles using standard tables. BW and AFI centiles were analyzed in diabetic patients with poor glycemic control using linear regression and ANOVA, with P < .05 significant. Results: In the poorly controlled diabetic population, a linear relationship existed between AFI and BW centiles, with the largest BW centiles having the highest AFI centiles (P < .0001). Conclusion: The previously noted relationship between elevated AFI and BW centiles in the general patient population is linear in diabetic patients with poor glycemic control.

Original languageEnglish (US)
Pages (from-to)848-850
Number of pages3
JournalAmerican journal of obstetrics and gynecology
Volume195
Issue number3
DOIs
StatePublished - Sep 1 2006
Externally publishedYes

Keywords

  • Amniotic fluid index
  • Birth weight
  • Diabetes
  • Macrosomia
  • Polyhydramnios

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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