An economic and practical synthesis of the 2-tetrahydrofuranyl ether protective group

J R Falck, De Run Li, Romain Bejot, Charles Mioskowski

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19 Scopus citations

Abstract

Primary, secondary, and tertiary alcohols as well as phenols and carbohydrates are efficiently transformed into the corresponding 2-tetrahydrofuranyl ethers by a combination of Mn(0) powder and CCl4 in tetrahydrofuran.

Original languageEnglish (US)
Pages (from-to)5111-5113
Number of pages3
JournalTetrahedron Letters
Volume47
Issue number29
DOIs
StatePublished - Jul 17 2006

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Keywords

  • Manganese
  • Protecting group
  • Radical reaction
  • Tetrahydrofuran

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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