An electrophoretic difference between surface and secreted IgM of murine splenocytes

U. Melcher, J. W. Uhr

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17 Scopus citations


μ chains on the surface of murine splenocytes are more heterogeneous on SDS polyacrylamide gel electrophoresis than both secreted and intracellular μ chains labeled with [3H]tyrosine. No difference in heterogeneity among cell surface, secreted, or intracellular L chains was detected. The possible role of carbohydrate in μ chain heterogeneity is discussed.

Original languageEnglish (US)
Pages (from-to)1282-1287
Number of pages6
JournalJournal of Experimental Medicine
Issue number5
Publication statusPublished - 1973


ASJC Scopus subject areas

  • Immunology

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