TY - JOUR
T1 - An enzyme that catalyzes hydrolysis of fructose-2,6-bisphosphate
AU - Furuya, Eisuke
AU - Yokoyama, Motoko
AU - Uyeda, Kosaku
N1 - Funding Information:
This work was supported by the Veterans Administration Research Service and by United States Public Health Service grant AM16194.
PY - 1982/3/15
Y1 - 1982/3/15
N2 - The enzyme which catalyzes the hydrolysis of fructose-2,6-P2 has been partially purified from rat liver. The product has been identified as fructose-6-P. The enzyme requires Mg++, and the K0.5 for fructose-2, 6-P2 varies from 25 - 100 μM, depending upon the preparation. After treatment with cAMP dependent protein kinase the enzyme is activated and the K0.5 for the substrate is lowered to 7 μM.
AB - The enzyme which catalyzes the hydrolysis of fructose-2,6-P2 has been partially purified from rat liver. The product has been identified as fructose-6-P. The enzyme requires Mg++, and the K0.5 for fructose-2, 6-P2 varies from 25 - 100 μM, depending upon the preparation. After treatment with cAMP dependent protein kinase the enzyme is activated and the K0.5 for the substrate is lowered to 7 μM.
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U2 - 10.1016/S0006-291X(82)80040-5
DO - 10.1016/S0006-291X(82)80040-5
M3 - Article
C2 - 6284147
AN - SCOPUS:0020482827
SN - 0006-291X
VL - 105
SP - 264
EP - 270
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 1
ER -