An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna

Phillip A. Dumesic, Daniel F. Egan, Philipp Gut, Mei T. Tran, Alice Parisi, Nirmalya Chatterjee, Mark Jedrychowski, Margherita Paschini, Lawrence Kazak, Sarah E. Wilensky, Florence Dou, Dina Bogoslavski, Jeffrey A. Cartier, Norbert Perrimon, Shingo Kajimura, Samir M. Parikh, Bruce M. Spiegelman

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Keywords

  • 5’ untranslated region
  • bluefin tuna
  • evolution
  • ischemic kidney injury
  • metabolism
  • mitochondria
  • oxidative phosphorylation
  • PGC1α
  • translational regulation
  • upstream open reading frame

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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