An implantable batteryless wireless impedance sensor for gastroesophageal reflux diagnosis

Thermpon Ativanichayaphong, Shou Jian Tang, Lun Chen Hsu, Wen Ding Huang, Young Sik Seo, H. F. Tibbals, Stuart Spechler, J. C. Chiao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

21 Scopus citations

Abstract

A new method for long term monitoring of gastroesophageal reflux is presented. The impedance of the reflux in the esophagus can be determined remotely without the need of a battery in the sensor implant. The implant includes an energy harvesting circuit, sensing electrodes, an antenna and an impedance to frequency converter. An external reader provides power to the implant and measures the impedance values simultaneously. A prototype with an overall size of 0.5×1×3.lcm3 was made with a printed circuit board and discrete components, and packaged in polydimethylsiloxane. In vivo experiments were conducted in pig cadavers. The results show good correlation between impedance and pH values of the acid solutions flushed into the esophagus, and good signal-to-noise ratios with the transducer inside the body. The impedance sensor can detect nonacid materials due to the frequency shift differences between air and solutions. The battery less wireless impedance sensor is able to detect every reflux episode, either acid or non-acid, which provides more accurate diagnosis for the gastroesophageal reflux disease.

Original languageEnglish (US)
Title of host publication2010 IEEE MTT-S International Microwave Symposium, MTT 2010
Pages608-611
Number of pages4
DOIs
StatePublished - Oct 15 2010
Event2010 IEEE MTT-S International Microwave Symposium, MTT 2010 - Anaheim, CA, United States
Duration: May 23 2010May 28 2010

Publication series

NameIEEE MTT-S International Microwave Symposium Digest
ISSN (Print)0149-645X

Other

Other2010 IEEE MTT-S International Microwave Symposium, MTT 2010
CountryUnited States
CityAnaheim, CA
Period5/23/105/28/10

Keywords

  • Batteryless
  • GERD
  • Impedance
  • Medical implant
  • RFID
  • Wireless

ASJC Scopus subject areas

  • Radiation
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

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  • Cite this

    Ativanichayaphong, T., Tang, S. J., Hsu, L. C., Huang, W. D., Seo, Y. S., Tibbals, H. F., Spechler, S., & Chiao, J. C. (2010). An implantable batteryless wireless impedance sensor for gastroesophageal reflux diagnosis. In 2010 IEEE MTT-S International Microwave Symposium, MTT 2010 (pp. 608-611). [5516775] (IEEE MTT-S International Microwave Symposium Digest). https://doi.org/10.1109/MWSYM.2010.5516775