An 'oligarchy' rules neural development

David H. Rowitch, Q. Richard Lu, Nicoletta Kessaris, William D. Richardson

Research output: Contribution to journalArticle

137 Citations (Scopus)

Abstract

Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.

Original languageEnglish (US)
Pages (from-to)417-422
Number of pages6
JournalTrends in Neurosciences
Volume25
Issue number8
DOIs
StatePublished - Aug 1 2002

Fingerprint

Oligodendroglia
Basic Helix-Loop-Helix Transcription Factors
Motor Neurons
Neuroglia
Neurons
Genes

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Rowitch, D. H., Lu, Q. R., Kessaris, N., & Richardson, W. D. (2002). An 'oligarchy' rules neural development. Trends in Neurosciences, 25(8), 417-422. https://doi.org/10.1016/S0166-2236(02)02201-4

An 'oligarchy' rules neural development. / Rowitch, David H.; Lu, Q. Richard; Kessaris, Nicoletta; Richardson, William D.

In: Trends in Neurosciences, Vol. 25, No. 8, 01.08.2002, p. 417-422.

Research output: Contribution to journalArticle

Rowitch, DH, Lu, QR, Kessaris, N & Richardson, WD 2002, 'An 'oligarchy' rules neural development', Trends in Neurosciences, vol. 25, no. 8, pp. 417-422. https://doi.org/10.1016/S0166-2236(02)02201-4
Rowitch DH, Lu QR, Kessaris N, Richardson WD. An 'oligarchy' rules neural development. Trends in Neurosciences. 2002 Aug 1;25(8):417-422. https://doi.org/10.1016/S0166-2236(02)02201-4
Rowitch, David H. ; Lu, Q. Richard ; Kessaris, Nicoletta ; Richardson, William D. / An 'oligarchy' rules neural development. In: Trends in Neurosciences. 2002 ; Vol. 25, No. 8. pp. 417-422.
@article{44ca4e46737640a9be34c84e6f7f7ee8,
title = "An 'oligarchy' rules neural development",
abstract = "Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.",
author = "Rowitch, {David H.} and Lu, {Q. Richard} and Nicoletta Kessaris and Richardson, {William D.}",
year = "2002",
month = "8",
day = "1",
doi = "10.1016/S0166-2236(02)02201-4",
language = "English (US)",
volume = "25",
pages = "417--422",
journal = "Trends in Neurosciences",
issn = "0378-5912",
publisher = "Elsevier Limited",
number = "8",

}

TY - JOUR

T1 - An 'oligarchy' rules neural development

AU - Rowitch, David H.

AU - Lu, Q. Richard

AU - Kessaris, Nicoletta

AU - Richardson, William D.

PY - 2002/8/1

Y1 - 2002/8/1

N2 - Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.

AB - Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.

UR - http://www.scopus.com/inward/record.url?scp=0036680383&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036680383&partnerID=8YFLogxK

U2 - 10.1016/S0166-2236(02)02201-4

DO - 10.1016/S0166-2236(02)02201-4

M3 - Article

C2 - 12127759

AN - SCOPUS:0036680383

VL - 25

SP - 417

EP - 422

JO - Trends in Neurosciences

JF - Trends in Neurosciences

SN - 0378-5912

IS - 8

ER -