An 'oligarchy' rules neural development

David H. Rowitch, Q. Richard Lu, Nicoletta Kessaris, William D. Richardson

Research output: Contribution to journalReview article

138 Scopus citations

Abstract

Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.

Original languageEnglish (US)
Pages (from-to)417-422
Number of pages6
JournalTrends in Neurosciences
Volume25
Issue number8
DOIs
StatePublished - Aug 1 2002

ASJC Scopus subject areas

  • Neuroscience(all)

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    Rowitch, D. H., Lu, Q. R., Kessaris, N., & Richardson, W. D. (2002). An 'oligarchy' rules neural development. Trends in Neurosciences, 25(8), 417-422. https://doi.org/10.1016/S0166-2236(02)02201-4