TY - JOUR
T1 - An 'oligarchy' rules neural development
AU - Rowitch, David H.
AU - Lu, Q. Richard
AU - Kessaris, Nicoletta
AU - Richardson, William D.
PY - 2002/8/1
Y1 - 2002/8/1
N2 - Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.
AB - Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.
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UR - http://www.scopus.com/inward/citedby.url?scp=0036680383&partnerID=8YFLogxK
U2 - 10.1016/S0166-2236(02)02201-4
DO - 10.1016/S0166-2236(02)02201-4
M3 - Review article
C2 - 12127759
AN - SCOPUS:0036680383
SN - 0166-2236
VL - 25
SP - 417
EP - 422
JO - Trends in Neurosciences
JF - Trends in Neurosciences
IS - 8
ER -