An unusually “complex” glomerulonephritis

Gabriela Martinez-Zayas, Daniel Savino, Sumit Kumar, Kathryn H. Dao

Research output: Contribution to journalArticlepeer-review

Abstract

A 53-year-old man with granulomatosis with polyangiitis presented with fever and acute kidney injury with nephrotic-range proteinuria following the second dose of the mRNA COVID-19 vaccine. Renal biopsy revealed an unexpected immune complex-glomerulonephritis (IC-GN) without vasculitis. Further workup found the patient to have HIV that was unmasked following the treatment of IC-GN. This case report explores the possible relationship between COVID-19 vaccines and the immune response in the setting of chronic HIV.

Original languageEnglish (US)
JournalBaylor University Medical Center Proceedings
DOIs
StateAccepted/In press - 2022

Keywords

  • COVID vaccine
  • glomerulonephritis
  • granulomatosis with polyangiitis
  • human immunodeficiency virus
  • immune complexes
  • type III hypersensitivity

ASJC Scopus subject areas

  • Medicine(all)

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