Anaesthesia for electroconvulsive therapy: Use of propofol revisited

B. Fredman, M. M. Husain, P. F. White

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In three clinically depressed patients undergoing repeated electroconvulsive therapy (ECT) with either propofol or methohexitone, dose-dependent decreases in the duration of motor and EEG seizure activity were noted. Use of a 'minimally' hypnotic dose of propofol (0.75-1.0 mg kg-1) was associated with a seizure duration which was comparable to standard hypnotic doses of methohexitone. We conclude that doses of propofol < 1.5 mg kg-1 are associated with a clinically acceptable duration of EEG seizure activity (> 30 s) during ECT.

Original languageEnglish (US)
Pages (from-to)423-425
Number of pages3
JournalEuropean Journal of Anaesthesiology
Volume11
Issue number5
StatePublished - 1994

Fingerprint

Electroconvulsive Therapy
Propofol
Methohexital
Anesthesia
Hypnotics and Sedatives
Seizures
Electroencephalography

Keywords

  • Anaesthesia
  • Electroconvulsive therapy
  • Intravenous anaesthetics
  • Methohexitone
  • Propofol
  • Seizure duration
  • Seizure threshold

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Anaesthesia for electroconvulsive therapy : Use of propofol revisited. / Fredman, B.; Husain, M. M.; White, P. F.

In: European Journal of Anaesthesiology, Vol. 11, No. 5, 1994, p. 423-425.

Research output: Contribution to journalArticle

@article{8e1758eb7c88409da76ae11dbca95623,
title = "Anaesthesia for electroconvulsive therapy: Use of propofol revisited",
abstract = "In three clinically depressed patients undergoing repeated electroconvulsive therapy (ECT) with either propofol or methohexitone, dose-dependent decreases in the duration of motor and EEG seizure activity were noted. Use of a 'minimally' hypnotic dose of propofol (0.75-1.0 mg kg-1) was associated with a seizure duration which was comparable to standard hypnotic doses of methohexitone. We conclude that doses of propofol < 1.5 mg kg-1 are associated with a clinically acceptable duration of EEG seizure activity (> 30 s) during ECT.",
keywords = "Anaesthesia, Electroconvulsive therapy, Intravenous anaesthetics, Methohexitone, Propofol, Seizure duration, Seizure threshold",
author = "B. Fredman and Husain, {M. M.} and White, {P. F.}",
year = "1994",
language = "English (US)",
volume = "11",
pages = "423--425",
journal = "European Journal of Anaesthesiology",
issn = "0265-0215",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Anaesthesia for electroconvulsive therapy

T2 - Use of propofol revisited

AU - Fredman, B.

AU - Husain, M. M.

AU - White, P. F.

PY - 1994

Y1 - 1994

N2 - In three clinically depressed patients undergoing repeated electroconvulsive therapy (ECT) with either propofol or methohexitone, dose-dependent decreases in the duration of motor and EEG seizure activity were noted. Use of a 'minimally' hypnotic dose of propofol (0.75-1.0 mg kg-1) was associated with a seizure duration which was comparable to standard hypnotic doses of methohexitone. We conclude that doses of propofol < 1.5 mg kg-1 are associated with a clinically acceptable duration of EEG seizure activity (> 30 s) during ECT.

AB - In three clinically depressed patients undergoing repeated electroconvulsive therapy (ECT) with either propofol or methohexitone, dose-dependent decreases in the duration of motor and EEG seizure activity were noted. Use of a 'minimally' hypnotic dose of propofol (0.75-1.0 mg kg-1) was associated with a seizure duration which was comparable to standard hypnotic doses of methohexitone. We conclude that doses of propofol < 1.5 mg kg-1 are associated with a clinically acceptable duration of EEG seizure activity (> 30 s) during ECT.

KW - Anaesthesia

KW - Electroconvulsive therapy

KW - Intravenous anaesthetics

KW - Methohexitone

KW - Propofol

KW - Seizure duration

KW - Seizure threshold

UR - http://www.scopus.com/inward/record.url?scp=0028041163&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028041163&partnerID=8YFLogxK

M3 - Article

C2 - 7988589

AN - SCOPUS:0028041163

VL - 11

SP - 423

EP - 425

JO - European Journal of Anaesthesiology

JF - European Journal of Anaesthesiology

SN - 0265-0215

IS - 5

ER -