Abstract
Drug-induced anaphylaxis is a common cause of anaphylaxis and a leading cause of fatal anaphylaxis. Antibiotics, radiocontrast, and nonsteroidal anti-inflammatory drugs are commonly implicated drugs. Vocal cord dysfunction can mimic anaphylaxis and is often overlooked. β-Lactams are a common cause of anaphylaxis; however, skin testing and drug challenge can usually determine tolerability of other classes of β-lactams. Nonionic contrast agents cause anaphylaxis less frequently than ionic contrast, and immunoglobulin E-mediated mechanisms may have a role in some of these reactions. Skin testing with radiocontrast may have a role in evaluating patients with anaphylaxis to nonionic contrast.
Original language | English (US) |
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Pages (from-to) | 303-319 |
Number of pages | 17 |
Journal | Immunology and Allergy Clinics of North America |
Volume | 35 |
Issue number | 2 |
DOIs | |
State | Published - May 1 2015 |
Keywords
- Anaphylaxis
- Cephalosporin
- Drug
- NSAID
- Penicillin
- Proton pump inhibitor
- Radiocontrast
- Vocal cord dysfunction
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology