TY - JOUR
T1 - Anatomic features of the optic disc and risk of progression in ocular hypertension
AU - Stewart, W. C.
AU - Connor, A. B.
AU - Wang -h., X.
PY - 1995/6
Y1 - 1995/6
N2 - ABSTRACT We evaluated characteristics of the optic disc in ocular hypertensive patients which might portend future glaucomatous damage. We included in this study 12 patients with an intraocular pressure > 21 mmHg who on follow‐up showed signs of optic nerve head damage. Each of these patients were matched to an ocular hypertensive patient who remained stable for > 5 years. This study found that neither optic disc, neural rim or peripapillary halo areas, vein or artery diameter over non‐atrophied or atrophied retinal areas, differed significantly between groups (p > 0.05, Wilcoxon signed rank test). However, peripapillary atrophy was greater in patients who showed signs of glaucomatous disc damage (1.757 ± 0.36 mm2, p = 0.02, Wilcoxon signed rank test) compared to stable patients (1.064 ± 0.79 mm2), although this finding was not significant after the Bonferroni correction. Patients with < 0.6 mm2 area of peripapillary atrophy (n = 6), however, did not suffer damage. This study suggests that a relationship between the extent of peripapillary atrophy and the chance of developing optic disc damage in patients with ocular hypertension deserves further study. 1995 Institution Acta Ophthalmologica Scandinavica
AB - ABSTRACT We evaluated characteristics of the optic disc in ocular hypertensive patients which might portend future glaucomatous damage. We included in this study 12 patients with an intraocular pressure > 21 mmHg who on follow‐up showed signs of optic nerve head damage. Each of these patients were matched to an ocular hypertensive patient who remained stable for > 5 years. This study found that neither optic disc, neural rim or peripapillary halo areas, vein or artery diameter over non‐atrophied or atrophied retinal areas, differed significantly between groups (p > 0.05, Wilcoxon signed rank test). However, peripapillary atrophy was greater in patients who showed signs of glaucomatous disc damage (1.757 ± 0.36 mm2, p = 0.02, Wilcoxon signed rank test) compared to stable patients (1.064 ± 0.79 mm2), although this finding was not significant after the Bonferroni correction. Patients with < 0.6 mm2 area of peripapillary atrophy (n = 6), however, did not suffer damage. This study suggests that a relationship between the extent of peripapillary atrophy and the chance of developing optic disc damage in patients with ocular hypertension deserves further study. 1995 Institution Acta Ophthalmologica Scandinavica
KW - chronic open‐angle glaucoma
KW - glaucoma suspect
KW - ocular hypertension
KW - optic disc
KW - peripapillary atrophy
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U2 - 10.1111/j.1600-0420.1995.tb00275.x
DO - 10.1111/j.1600-0420.1995.tb00275.x
M3 - Article
C2 - 7493235
AN - SCOPUS:0029055665
SN - 1395-3907
VL - 73
SP - 237
EP - 241
JO - Acta Ophthalmologica Scandinavica
JF - Acta Ophthalmologica Scandinavica
IS - 3
ER -