Anatomic features of the optic disc and risk of progression in ocular hypertension

W. C. Stewart, A. B. Connor, X. Wang -h.

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


ABSTRACT We evaluated characteristics of the optic disc in ocular hypertensive patients which might portend future glaucomatous damage. We included in this study 12 patients with an intraocular pressure > 21 mmHg who on follow‐up showed signs of optic nerve head damage. Each of these patients were matched to an ocular hypertensive patient who remained stable for > 5 years. This study found that neither optic disc, neural rim or peripapillary halo areas, vein or artery diameter over non‐atrophied or atrophied retinal areas, differed significantly between groups (p > 0.05, Wilcoxon signed rank test). However, peripapillary atrophy was greater in patients who showed signs of glaucomatous disc damage (1.757 ± 0.36 mm2, p = 0.02, Wilcoxon signed rank test) compared to stable patients (1.064 ± 0.79 mm2), although this finding was not significant after the Bonferroni correction. Patients with < 0.6 mm2 area of peripapillary atrophy (n = 6), however, did not suffer damage. This study suggests that a relationship between the extent of peripapillary atrophy and the chance of developing optic disc damage in patients with ocular hypertension deserves further study. 1995 Institution Acta Ophthalmologica Scandinavica

Original languageEnglish (US)
Pages (from-to)237-241
Number of pages5
JournalActa Ophthalmologica Scandinavica
Issue number3
StatePublished - Jun 1995


  • chronic open‐angle glaucoma
  • glaucoma suspect
  • ocular hypertension
  • optic disc
  • peripapillary atrophy

ASJC Scopus subject areas

  • Ophthalmology


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