Animal models of spondyloarthritis

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Scopus citations

Abstract

Animal models are available for the studyof several different aspects of spondyloarthritis. The models include naturally occurring spontaneous disorders in primates and rodents, spon taneous disorders in transgenic or gene-deleted rodents and induced disorders inrodents. Areas ofinvestigation to which these models contribute include the role HLA-B27,processes of spinal and peripheral joint inflammation and calcification, immune responsesto candidate antigens and the role of TNF.

Original languageEnglish (US)
Title of host publicationMolecular Mechanisms of Spondyloarthropathies
EditorsCarlos Lopez-Larrea, Roberto Diaz-Pena
Pages245-254
Number of pages10
DOIs
StatePublished - Dec 1 2009

Publication series

NameAdvances in Experimental Medicine and Biology
Volume649
ISSN (Print)0065-2598

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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