Anthrax as a biological weapon: Medical and public health management

Thomas V. Inglesby, Donald A. Henderson, John G. Bartlett, Michael S. Ascher, Edward Eitzen, Arthur M. Friedlander, Jerome Hauer, Joseph McDade, Michael T. Osterholm, Tara O'Toole, Gerald Parker, Trish M. Perl, Philip K. Russell, Kevin Tonat

Research output: Contribution to journalReview article

671 Citations (Scopus)

Abstract

Objective To develop consensus-based recommendations for measures to be taken by medical and public health professionals following the use of anthrax as a biological weapon against a civilian population. Participants The working group included 21 representatives from staff of major academic medical centers and research, government, military, public health, and emergency management institutions and agencies. Evidence MEDLINE databases were searched from January 1966 to April 1998, using the Medical Subject Headings anthrax, Bacillus anthracis biological weapon, biological terrorism, biological warfare, and biowarfare. Review of references identified by this search led to identification of relevant references published prior to 1966. In addition participants identified other unpublished references and sources. Consensus Process The first draft of the consensus statement was a synthesis of information obtained in the formal evidence-gathering process. Members of the working group provided formal written comments which were incorporated into the second draft of the statement. The working group reviewed the second draft on June 12, 1998. No significant disagreements existed and comments were incorporated into a third draft. The fourth and final statement incorporates all relevant evidence obtained by the literature search in conjunction with final consensus recommendations supported by all working group members. Conclusions Specific consensus recommendations are made regarding the diagnosis of anthrax, indications for vaccination, therapy for those exposed, postexposure prophylaxis, decontamination of the environment, and additional research needs.

Original languageEnglish (US)
Pages (from-to)1735-1745
Number of pages11
JournalJournal of the American Medical Association
Volume281
Issue number18
DOIs
StatePublished - May 12 1999

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Biological Warfare Agents
Anthrax
Public Health
Biological Warfare
Medical Subject Headings
Bioterrorism
Bacillus anthracis
Decontamination
MEDLINE
Biomedical Research
Vaccination
Emergencies
Databases
Research
Population
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Inglesby, T. V., Henderson, D. A., Bartlett, J. G., Ascher, M. S., Eitzen, E., Friedlander, A. M., ... Tonat, K. (1999). Anthrax as a biological weapon: Medical and public health management. Journal of the American Medical Association, 281(18), 1735-1745. https://doi.org/10.1001/jama.281.18.1735

Anthrax as a biological weapon : Medical and public health management. / Inglesby, Thomas V.; Henderson, Donald A.; Bartlett, John G.; Ascher, Michael S.; Eitzen, Edward; Friedlander, Arthur M.; Hauer, Jerome; McDade, Joseph; Osterholm, Michael T.; O'Toole, Tara; Parker, Gerald; Perl, Trish M.; Russell, Philip K.; Tonat, Kevin.

In: Journal of the American Medical Association, Vol. 281, No. 18, 12.05.1999, p. 1735-1745.

Research output: Contribution to journalReview article

Inglesby, TV, Henderson, DA, Bartlett, JG, Ascher, MS, Eitzen, E, Friedlander, AM, Hauer, J, McDade, J, Osterholm, MT, O'Toole, T, Parker, G, Perl, TM, Russell, PK & Tonat, K 1999, 'Anthrax as a biological weapon: Medical and public health management', Journal of the American Medical Association, vol. 281, no. 18, pp. 1735-1745. https://doi.org/10.1001/jama.281.18.1735
Inglesby TV, Henderson DA, Bartlett JG, Ascher MS, Eitzen E, Friedlander AM et al. Anthrax as a biological weapon: Medical and public health management. Journal of the American Medical Association. 1999 May 12;281(18):1735-1745. https://doi.org/10.1001/jama.281.18.1735
Inglesby, Thomas V. ; Henderson, Donald A. ; Bartlett, John G. ; Ascher, Michael S. ; Eitzen, Edward ; Friedlander, Arthur M. ; Hauer, Jerome ; McDade, Joseph ; Osterholm, Michael T. ; O'Toole, Tara ; Parker, Gerald ; Perl, Trish M. ; Russell, Philip K. ; Tonat, Kevin. / Anthrax as a biological weapon : Medical and public health management. In: Journal of the American Medical Association. 1999 ; Vol. 281, No. 18. pp. 1735-1745.
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