Anti-epiligrin cicatricial pemphigoid and relative risk for cancer

Conleth A. Egan; Zelmira Lazarova; Thomas N. Darling; Carole Yee; Timothy Coté; Kim B. Yancey

doi:10.1016/S0140-6736(00)04971-0

Anti-epiligrin cicatricial pemphigoid and relative risk for cancer

Conleth A. Egan, Zelmira Lazarova, Thomas N. Darling, Carole Yee, Timothy Coté, Kim B. Yancey

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197 Scopus citations

Abstract

It is not known whether patients with anti-epiligrin cicatricial pemphigoid (AECP) have an increased risk of malignancy. We calculated the expected numbers of cancers in a cohort of 35 such patients based on respective incidence rates for all cancers in the National Cancer Institute's Surveillance, Epidemiology, and End Results (NCI SEER) Registry. Ten patients in this cohort had solitary solid cancers; eight patients developed cancer after onset of AECP (seven within 14 months). The relative risk (RR) for cancer in this cohort was 6·8 (95% confidence intervals [CI]: 3·3-12·5). AECP seems to be associated with an increased relative risk for cancer.

Original language	English (US)
Pages (from-to)	1850-1851
Number of pages	2
Journal	Lancet
Volume	357
Issue number	9271
DOIs	https://doi.org/10.1016/S0140-6736(00)04971-0
State	Published - Jun 9 2001

ASJC Scopus subject areas

General Medicine

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title = "Anti-epiligrin cicatricial pemphigoid and relative risk for cancer",

abstract = "It is not known whether patients with anti-epiligrin cicatricial pemphigoid (AECP) have an increased risk of malignancy. We calculated the expected numbers of cancers in a cohort of 35 such patients based on respective incidence rates for all cancers in the National Cancer Institute's Surveillance, Epidemiology, and End Results (NCI SEER) Registry. Ten patients in this cohort had solitary solid cancers; eight patients developed cancer after onset of AECP (seven within 14 months). The relative risk (RR) for cancer in this cohort was 6·8 (95% confidence intervals [CI]: 3·3-12·5). AECP seems to be associated with an increased relative risk for cancer.",

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T1 - Anti-epiligrin cicatricial pemphigoid and relative risk for cancer

AU - Egan, Conleth A.

AU - Lazarova, Zelmira

AU - Darling, Thomas N.

AU - Yee, Carole

AU - Coté, Timothy

AU - Yancey, Kim B.

PY - 2001/6/9

Y1 - 2001/6/9

N2 - It is not known whether patients with anti-epiligrin cicatricial pemphigoid (AECP) have an increased risk of malignancy. We calculated the expected numbers of cancers in a cohort of 35 such patients based on respective incidence rates for all cancers in the National Cancer Institute's Surveillance, Epidemiology, and End Results (NCI SEER) Registry. Ten patients in this cohort had solitary solid cancers; eight patients developed cancer after onset of AECP (seven within 14 months). The relative risk (RR) for cancer in this cohort was 6·8 (95% confidence intervals [CI]: 3·3-12·5). AECP seems to be associated with an increased relative risk for cancer.

AB - It is not known whether patients with anti-epiligrin cicatricial pemphigoid (AECP) have an increased risk of malignancy. We calculated the expected numbers of cancers in a cohort of 35 such patients based on respective incidence rates for all cancers in the National Cancer Institute's Surveillance, Epidemiology, and End Results (NCI SEER) Registry. Ten patients in this cohort had solitary solid cancers; eight patients developed cancer after onset of AECP (seven within 14 months). The relative risk (RR) for cancer in this cohort was 6·8 (95% confidence intervals [CI]: 3·3-12·5). AECP seems to be associated with an increased relative risk for cancer.

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Anti-epiligrin cicatricial pemphigoid and relative risk for cancer

Abstract

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