Anti-epiligrin cicatricial pemphigoid with IgG autoantibodies to the β and γ subunits of laminin 5

W. Fujimoto, Y. Toi, F. Okazaki, Z. Lazarova, K. B. Yancey, J. Arata

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Anti-epiligrin cicatricial pemphigoid is an autoimmune subepithelial blistering disorder of mucous membranes and skin. By immunoblot analyses, sera of most patients with anti-epiligrin cicatricial pemphigoid have been shown to react specifically with the α3 chain of laminin 5. We describe the first patient with anti-epiligrin cicatricial pemphigoid in whom circulating IgG autoantibodies directed against the β3 and γ2-chains of laminin 5 were detected. Treatment with oral prednisolone was beneficial in controlling the disease.

Original languageEnglish (US)
Pages (from-to)637-639
Number of pages3
JournalJournal of the American Academy of Dermatology
Volume40
Issue number4
DOIs
StatePublished - Jan 1 1999

ASJC Scopus subject areas

  • Dermatology

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