Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia

Cheng Lung Ku; Chia Hao Lin; Su Wei Chang; Chen Chung Chu; Jasper F.W. Chan; Xiao Fei Kong; Chen Hsiang Lee; Emily A. Rosen; Jing Ya Ding; Wen I. Lee; Jacinta Bustamante; Torsten Witte; Han Po Shih; Chen Yen Kuo; Ploenchan Chetchotisakd; Sasisopin Kiertiburanakul; Yupin Suputtamongkol; Kwok Yung Yuen; Jean Laurent Casanova; Steven M. Holland; Rainer Doffinger; Sarah K. Browne; Chih Yu Chi

doi:10.1016/j.jaci.2015.09.018

Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia

Cheng Lung Ku, Chia Hao Lin, Su Wei Chang, Chen Chung Chu, Jasper F.W. Chan, Xiao Fei Kong, Chen Hsiang Lee, Emily A. Rosen, Jing Ya Ding, Wen I. Lee, Jacinta Bustamante, Torsten Witte, Han Po Shih, Chen Yen Kuo, Ploenchan Chetchotisakd, Sasisopin Kiertiburanakul, Yupin Suputtamongkol, Kwok Yung Yuen, Jean Laurent Casanova, Steven M. HollandRainer Doffinger, Sarah K. Browne, Chih Yu Chi

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Original language	English (US)
Pages (from-to)	945-948.e8
Journal	Journal of Allergy and Clinical Immunology
Volume	137
Issue number	3
DOIs	https://doi.org/10.1016/j.jaci.2015.09.018
State	Published - Mar 1 2016
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/j.jaci.2015.09.018

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Ku, C. L., Lin, C. H., Chang, S. W., Chu, C. C., Chan, J. F. W., Kong, X. F., Lee, C. H., Rosen, E. A., Ding, J. Y., Lee, W. I., Bustamante, J., Witte, T., Shih, H. P., Kuo, C. Y., Chetchotisakd, P., Kiertiburanakul, S., Suputtamongkol, Y., Yuen, K. Y., Casanova, J. L., ... Chi, C. Y. (2016). Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia. Journal of Allergy and Clinical Immunology, 137(3), 945-948.e8. https://doi.org/10.1016/j.jaci.2015.09.018

Ku, CL, Lin, CH, Chang, SW, Chu, CC, Chan, JFW, Kong, XF, Lee, CH, Rosen, EA, Ding, JY, Lee, WI, Bustamante, J, Witte, T, Shih, HP, Kuo, CY, Chetchotisakd, P, Kiertiburanakul, S, Suputtamongkol, Y, Yuen, KY, Casanova, JL, Holland, SM, Doffinger, R, Browne, SK & Chi, CY 2016, 'Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia', Journal of Allergy and Clinical Immunology, vol. 137, no. 3, pp. 945-948.e8. https://doi.org/10.1016/j.jaci.2015.09.018

@article{61beb51bd91f4670a6a583cc2c2affb8,

title = "Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia",

author = "Ku, {Cheng Lung} and Lin, {Chia Hao} and Chang, {Su Wei} and Chu, {Chen Chung} and Chan, {Jasper F.W.} and Kong, {Xiao Fei} and Lee, {Chen Hsiang} and Rosen, {Emily A.} and Ding, {Jing Ya} and Lee, {Wen I.} and Jacinta Bustamante and Torsten Witte and Shih, {Han Po} and Kuo, {Chen Yen} and Ploenchan Chetchotisakd and Sasisopin Kiertiburanakul and Yupin Suputtamongkol and Yuen, {Kwok Yung} and Casanova, {Jean Laurent} and Holland, {Steven M.} and Rainer Doffinger and Browne, {Sarah K.} and Chi, {Chih Yu}",

note = "Funding Information: Disclosure of potential conflict of interest: C.-L. Ku has received research support from the Ministry of Science and Technology and Chang Gung Memorial Hospital. J. F. W. Chan has received research support from the Health and Medical Research Fund (grant no. 13121342) of the Food and Health Bureau of the Hong Kong Special Administrative Region Government; has received lecture fees from Gilead Sciences Hong Kong Ltd; and has received travel support from Pfizer Corporation Hong Kong Ltd, Astellas Pharma Hong Kong Co Ltd, and Gilead Sciences Hong Kong Ltd. P. Chetchotisakd has received research support from Gilead ( GS-US-292-0104 , GS-US-292-0109 , GS-US-292-0117 and GS-US-292-0112 ). J.-L. Casanova has received research support from the St Giles. The rest of the authors declare that they have no relevant conflicts of interest. Funding Information: This study was supported by grants from the National Health Research Institutes (grant no. NHRI-EX100-10028SC ), Ministry of Science and Technology (grant no. NSC102-2320-B-182-024 ), Chang Gung Memorial Hospital (grant no. CMRPD1D0061 ), and the Health and Medical Research Fund (grant no. 13121342 ) of the Food and Health Bureau of the Hong Kong Special Administrative Region Government. The Laboratory of Human Genetics of Infectious Diseases was supported by grants from the Rockefeller University, the St Giles Foundation, Institut National de la Sant{\'e} et de la Recherche M{\'e}dicale, University Paris Descartes, and the French National Research Agency (ANR) under the “Investments for the future” program (grant no. ANR-10-IAHU-01). ",

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language = "English (US)",

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T1 - Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia

AU - Ku, Cheng Lung

AU - Lin, Chia Hao

AU - Chang, Su Wei

AU - Chu, Chen Chung

AU - Chan, Jasper F.W.

AU - Kong, Xiao Fei

AU - Lee, Chen Hsiang

AU - Rosen, Emily A.

AU - Ding, Jing Ya

AU - Lee, Wen I.

AU - Bustamante, Jacinta

AU - Witte, Torsten

AU - Shih, Han Po

AU - Kuo, Chen Yen

AU - Chetchotisakd, Ploenchan

AU - Kiertiburanakul, Sasisopin

AU - Suputtamongkol, Yupin

AU - Yuen, Kwok Yung

AU - Casanova, Jean Laurent

AU - Holland, Steven M.

AU - Doffinger, Rainer

AU - Browne, Sarah K.

AU - Chi, Chih Yu

N1 - Funding Information: Disclosure of potential conflict of interest: C.-L. Ku has received research support from the Ministry of Science and Technology and Chang Gung Memorial Hospital. J. F. W. Chan has received research support from the Health and Medical Research Fund (grant no. 13121342) of the Food and Health Bureau of the Hong Kong Special Administrative Region Government; has received lecture fees from Gilead Sciences Hong Kong Ltd; and has received travel support from Pfizer Corporation Hong Kong Ltd, Astellas Pharma Hong Kong Co Ltd, and Gilead Sciences Hong Kong Ltd. P. Chetchotisakd has received research support from Gilead ( GS-US-292-0104 , GS-US-292-0109 , GS-US-292-0117 and GS-US-292-0112 ). J.-L. Casanova has received research support from the St Giles. The rest of the authors declare that they have no relevant conflicts of interest. Funding Information: This study was supported by grants from the National Health Research Institutes (grant no. NHRI-EX100-10028SC ), Ministry of Science and Technology (grant no. NSC102-2320-B-182-024 ), Chang Gung Memorial Hospital (grant no. CMRPD1D0061 ), and the Health and Medical Research Fund (grant no. 13121342 ) of the Food and Health Bureau of the Hong Kong Special Administrative Region Government. The Laboratory of Human Genetics of Infectious Diseases was supported by grants from the Rockefeller University, the St Giles Foundation, Institut National de la Santé et de la Recherche Médicale, University Paris Descartes, and the French National Research Agency (ANR) under the “Investments for the future” program (grant no. ANR-10-IAHU-01).

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Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia

ASJC Scopus subject areas

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