Antibiotic susceptibility of environmental Legionella pneumophila isolated in India

K. Sreenath, Rama Chaudhry, E. V. Vinayaraj, Bhaskar Thakur

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Aim: Data are limited regarding the antibiotic susceptibility of Legionella pneumophila in India. The aim of this study was to determine the drug susceptibility of environmental L. pneumophila isolates in India for antibiotics commonly used in clinical practice for Legionnaires' disease treatment. Materials & methods: The activities of seven antibiotics against 46 environmental isolates of L. pneumophila were evaluated by using E-test on buffered charcoal yeast extract-α agar. Results: Among the L. pneumophila isolates tested, no tendency toward drug resistance was observed. Rifampicin was the most potent drug followed by levofloxacin, while doxycycline and tetracycline were found to be the less active agents. Conclusion: Susceptibility testing of Legionella environmental isolates could be beneficial to notify resistance to antibiotics in the environment before it becomes evident in clinical strains.

Original languageEnglish (US)
Pages (from-to)661-669
Number of pages9
JournalFuture Microbiology
Volume14
Issue number8
DOIs
StatePublished - 2019
Externally publishedYes

Keywords

  • antibiotic susceptibility testing
  • drug resistance
  • E-test
  • fluoroquinolones
  • Legionella
  • Legionella pneumophila serogroup 1
  • macrolides
  • rifampicin
  • tetracyclines

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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