Antibody Testing in Peripheral Neuropathies

Steven Vernino, Gil I. Wolfe

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

There is a definite role for autoantibody testing in the evaluation of PN. The use and interpretation of antibody results always should depend on the clinical and electrophysiologic presentation of a patient. The presence of autoantibodies provides evidence of autoimmunity that may contribute to the pathophysiology of neuropathy. Some antibodies have clear significance in terms of guiding diagnosis (eg, paraneoplastic antibodies) or prognosis and treatment (eg, GM1 antibodies). Most of the autoantibodies, however, do not define a specific clinical syndrome and do not have a proved direct pathogenic role.

Original languageEnglish (US)
Pages (from-to)29-46
Number of pages18
JournalNeurologic Clinics
Volume25
Issue number1
DOIs
StatePublished - Feb 2007

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Peripheral Nervous System Diseases
Autoantibodies
Antibodies
Autoimmunity
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Antibody Testing in Peripheral Neuropathies. / Vernino, Steven; Wolfe, Gil I.

In: Neurologic Clinics, Vol. 25, No. 1, 02.2007, p. 29-46.

Research output: Contribution to journalArticle

Vernino, Steven ; Wolfe, Gil I. / Antibody Testing in Peripheral Neuropathies. In: Neurologic Clinics. 2007 ; Vol. 25, No. 1. pp. 29-46.
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