Antimicrobial agents in pediatrics.

M. M. Mustafa, G. H. McCracken

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

For proper use of antimicrobial agents in infants and children, special precautions should be taken. These include knowledge of the pharmacokinetic properties of these agents, especially in neonates, and of host factors related to gestational and chronological ages of the patient. Failure to recognize such factors can result in either lack of therapeutic response of drug-related adverse effects. In this article, special aspects of the pharmacokinetics of antibiotics and the clinical pharmacology and indications for use of the beta-lactam antibiotics in infants and children are presented.

Original languageEnglish (US)
Pages (from-to)491-506
Number of pages16
JournalInfectious Disease Clinics of North America
Volume3
Issue number3
StatePublished - Sep 1989

Fingerprint

Anti-Infective Agents
Pharmacokinetics
Pediatrics
Anti-Bacterial Agents
Clinical Pharmacology
beta-Lactams
Gestational Age
Newborn Infant
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Antimicrobial agents in pediatrics. / Mustafa, M. M.; McCracken, G. H.

In: Infectious Disease Clinics of North America, Vol. 3, No. 3, 09.1989, p. 491-506.

Research output: Contribution to journalArticle

@article{b28a7fada6a84524891a1dcd105980dc,
title = "Antimicrobial agents in pediatrics.",
abstract = "For proper use of antimicrobial agents in infants and children, special precautions should be taken. These include knowledge of the pharmacokinetic properties of these agents, especially in neonates, and of host factors related to gestational and chronological ages of the patient. Failure to recognize such factors can result in either lack of therapeutic response of drug-related adverse effects. In this article, special aspects of the pharmacokinetics of antibiotics and the clinical pharmacology and indications for use of the beta-lactam antibiotics in infants and children are presented.",
author = "Mustafa, {M. M.} and McCracken, {G. H.}",
year = "1989",
month = "9",
language = "English (US)",
volume = "3",
pages = "491--506",
journal = "Infectious Disease Clinics of North America",
issn = "0891-5520",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Antimicrobial agents in pediatrics.

AU - Mustafa, M. M.

AU - McCracken, G. H.

PY - 1989/9

Y1 - 1989/9

N2 - For proper use of antimicrobial agents in infants and children, special precautions should be taken. These include knowledge of the pharmacokinetic properties of these agents, especially in neonates, and of host factors related to gestational and chronological ages of the patient. Failure to recognize such factors can result in either lack of therapeutic response of drug-related adverse effects. In this article, special aspects of the pharmacokinetics of antibiotics and the clinical pharmacology and indications for use of the beta-lactam antibiotics in infants and children are presented.

AB - For proper use of antimicrobial agents in infants and children, special precautions should be taken. These include knowledge of the pharmacokinetic properties of these agents, especially in neonates, and of host factors related to gestational and chronological ages of the patient. Failure to recognize such factors can result in either lack of therapeutic response of drug-related adverse effects. In this article, special aspects of the pharmacokinetics of antibiotics and the clinical pharmacology and indications for use of the beta-lactam antibiotics in infants and children are presented.

UR - http://www.scopus.com/inward/record.url?scp=0024727875&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024727875&partnerID=8YFLogxK

M3 - Article

VL - 3

SP - 491

EP - 506

JO - Infectious Disease Clinics of North America

JF - Infectious Disease Clinics of North America

SN - 0891-5520

IS - 3

ER -