Antiproton therapy

Helge V. Knudsen, Michael H. Holzscheiter, Niels Bassler, Jan Alsner, Gerd Beyer, John J. DeMarco, Michael Doser, Dragan Hajdukovic, Oliver Hartley, Keisuke S. Iwamoto, Oliver Jäkel, Sandra Kovacevic, Søren Pape Møller, Jens Overgaard, Jørgen B. Petersen, Osman Ratib, Timothy D. Solberg, Sanja Vranjes, Bradly G. Wouters

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Radiotherapy is one of the most important means we have for the treatment of localised tumours. It is therefore essential to optimize the technique, and a lot of effort goes into this endeavour. Since the proposal by Wilson in 1946 [R.R. Wilson, Radiology use of fast protons, Radiology 47 (1946) 487.] that proton beams might be better than photon beams at inactivating cancer cells, hadron therapy has been developed in parallel with photon therapy and a substantial knowledge has been gained on the effects of pions, protons and heavy ions (mostly carbon ions). Here we discuss the recent measurements by the CERN ACE collaboration of the biological effects of antiprotons, and argue that these particles very likely are the optimal agents for radiotherapy.

Original languageEnglish (US)
Pages (from-to)530-534
Number of pages5
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume266
Issue number3
DOIs
StatePublished - Feb 2008

Keywords

  • Antiproton
  • CERN
  • Radiation therapy

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation

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    Knudsen, H. V., Holzscheiter, M. H., Bassler, N., Alsner, J., Beyer, G., DeMarco, J. J., Doser, M., Hajdukovic, D., Hartley, O., Iwamoto, K. S., Jäkel, O., Kovacevic, S., Møller, S. P., Overgaard, J., Petersen, J. B., Ratib, O., Solberg, T. D., Vranjes, S., & Wouters, B. G. (2008). Antiproton therapy. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 266(3), 530-534. https://doi.org/10.1016/j.nimb.2007.12.035