TY - JOUR
T1 - Aortic endograft surveillance
T2 - Use of fast-switch kVp dual-energy computed tomography with virtual noncontrast imaging
AU - Maturen, Katherine E.
AU - Kleaveland, Patricia A.
AU - Kaza, Ravi K.
AU - Liu, Peter S.
AU - Quint, Leslie E.
AU - Khalatbari, Shokoufeh H.
AU - Platt, Joel F.
PY - 2011
Y1 - 2011
N2 - OBJECTIVE: To assess endoleak detection and patients' radiation exposure using fast-switch peak kilovoltage (kVp) dual-energy computed tomography (DECT) with virtual noncontrast (VNC) imaging. METHODS: Institutional review board approved retrospective review of triphasic CTs for endograft follow-up: single-energy true noncontrast (TNC) and dual-energy arterial- and venous-phase postcontrast scans on GE HD-750 64-detector scanners. Iodine-subtracted VNC images generated from dual-energy data. Two radiologists (VNC readers) independently performed 2 reading sessions without TNC images: (1) arterial and VNC and (2) venous and VNC. Interrater agreement, leak detection sensitivity, and dose estimates were calculated. RESULTS: Original dictations described 24 endoleaks in 78 scans. Virtual noncontrast reader agreement was high (κ = 0.78-0.79). Virtual noncontrast reader ranges for sensitivity and negative predictive value for leak detection were 87.5% to 95.8% and 94.0% to 98.0% in venous phase. Dose reduction estimate was 40% by eliminating one phase and 64% by eliminating 2 phases of imaging. CONCLUSION: Virtual noncontrast images from fast-switch peak kilovoltage DECT data can substitute for TNC imaging in the postendograft aorta, conferring substantial dose reduction. Eliminating 1 of 2 postcontrast phases further reduces dose, with greater negative predictive value for leak detection in the venous versus the arterial phase. Thus, the use of a monophasic venous-phase DECT with VNC images is suggested for long-term endograft surveillance in stable patients.
AB - OBJECTIVE: To assess endoleak detection and patients' radiation exposure using fast-switch peak kilovoltage (kVp) dual-energy computed tomography (DECT) with virtual noncontrast (VNC) imaging. METHODS: Institutional review board approved retrospective review of triphasic CTs for endograft follow-up: single-energy true noncontrast (TNC) and dual-energy arterial- and venous-phase postcontrast scans on GE HD-750 64-detector scanners. Iodine-subtracted VNC images generated from dual-energy data. Two radiologists (VNC readers) independently performed 2 reading sessions without TNC images: (1) arterial and VNC and (2) venous and VNC. Interrater agreement, leak detection sensitivity, and dose estimates were calculated. RESULTS: Original dictations described 24 endoleaks in 78 scans. Virtual noncontrast reader agreement was high (κ = 0.78-0.79). Virtual noncontrast reader ranges for sensitivity and negative predictive value for leak detection were 87.5% to 95.8% and 94.0% to 98.0% in venous phase. Dose reduction estimate was 40% by eliminating one phase and 64% by eliminating 2 phases of imaging. CONCLUSION: Virtual noncontrast images from fast-switch peak kilovoltage DECT data can substitute for TNC imaging in the postendograft aorta, conferring substantial dose reduction. Eliminating 1 of 2 postcontrast phases further reduces dose, with greater negative predictive value for leak detection in the venous versus the arterial phase. Thus, the use of a monophasic venous-phase DECT with VNC images is suggested for long-term endograft surveillance in stable patients.
KW - aorta
KW - dual-energy CT
KW - endograft surveillance
KW - endoleak detection
KW - virtual noncontrast imaging
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U2 - 10.1097/RCT.0b013e3182372c14
DO - 10.1097/RCT.0b013e3182372c14
M3 - Article
C2 - 22082546
AN - SCOPUS:81355123472
SN - 0363-8715
VL - 35
SP - 742
EP - 746
JO - Journal of computer assisted tomography
JF - Journal of computer assisted tomography
IS - 6
ER -