Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview

Hans H. Bock, Joachim Herz

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

It is now well established that members of the low-density lipoprotein (LDL) receptor gene family are crucial regulators of different aspects of neuronal development, synaptic plasticity, maintenance of neuronal homeostasis, and neurodegeneration. This was highlighted in particular by the discovery that the lipoprotein receptors apolipoprotein E receptor-2 (ApoER2) and very-low-density lipoprotein receptor (VLDLR) function as receptors for the neuronal signaling protein Reelin. In this chapter, we will briefly introduce the family of LDL receptor-related proteins and review the functions of its members ApoER2 and VLDLR as Reelin receptors and their role in the developing and adult brain.

Original languageEnglish (US)
Title of host publicationReelin Glycoprotein: Structure, Biology and Roles in Health and Disease
PublisherSpringer New York
Pages15-35
Number of pages21
ISBN (Print)9780387767611, 9780387767604
DOIs
StatePublished - 2008

Fingerprint

Apolipoproteins
LDL Receptors
LDL-Receptor Related Proteins
Lipoprotein Receptors
Neuronal Plasticity
Homeostasis
Maintenance
Brain
Genes
low density lipoprotein receptor-related protein 8
VLDL receptor
reelin protein
reelin receptor

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

Cite this

Bock, H. H., & Herz, J. (2008). Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview. In Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease (pp. 15-35). Springer New York. https://doi.org/10.1007/978-0-387-76761-1_2

Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor : An overview. / Bock, Hans H.; Herz, Joachim.

Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. Springer New York, 2008. p. 15-35.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bock, HH & Herz, J 2008, Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview. in Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. Springer New York, pp. 15-35. https://doi.org/10.1007/978-0-387-76761-1_2
Bock HH, Herz J. Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview. In Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. Springer New York. 2008. p. 15-35 https://doi.org/10.1007/978-0-387-76761-1_2
Bock, Hans H. ; Herz, Joachim. / Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor : An overview. Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. Springer New York, 2008. pp. 15-35
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